1. Gene
  2. Nox1 - NADPH oxidase 1 Gene

Nox1 - NADPH oxidase 1 Gene

中文名称:NADPH 氧化酶1

种属: Rattus norvegicus

基因 ID: 114243 | 基因类型: protein coding

关于 Nox1

Primary_assembly X: 97,279,056-97,302,236 reverse strand.mRatBN7.2:CM026994.1

This gene has 5 transcripts (splice variants), 126 orthologues, 5 paralogues and is associated with 8 phenotypes. Biased expression in Brain (RPKM 13.3), Thymus (RPKM 12.8) and 9 other tissues.

功能概要

该基因编码的蛋白可启动 NAD(P)H 氧化酶 H2O2 形成活性。参与多个过程,包括活性氧代谢过程的正向调节;平滑肌细胞增殖的正调节;和超氧阴离子的产生。 NADPH 氧化酶复合物的一部分。与人 NOX1(NADPH 氧化酶 1)同源。 [由基因组资源联盟提供,2022 年 4 月]

Enables NAD(P)H oxidase H2O2-forming activity. Involved in several processes, including positive regulation of Reactive Oxygen Species metabolic process; positive regulation of smooth muscle cell proliferation; and superoxide anion generation. Part of NADPH Oxidase complex. Orthologous to human NOX1 (NADPH Oxidase 1). [provided by Alliance of Genome Resources, Apr 2022]

Nox1 基因产物(1)

mRNA Protein Name
NM_053683.2 NP_446135.2 NADPH oxidase 1

Nox1 蛋白结构

Ferric_reduct

Ferric_reduct: pfam01794 (73 - 214)

NOX_Duox_like_FAD_NADP

NOX_Duox_like_FAD_NADP: cd06186 (295 - 562)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 500
  • 563 a.a.
蛋白主名 其他名称

NADPH oxidase 1

MOX-1

MOX1

NADH/NADPH mitogenic oxidase subunit p65-mox

NOH-1

NOX-1

mitogenic oxidase 1

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Nox1 NCBI NCBI:27035