2. Gene
  3. Ido1 - indoleamine 2,3-dioxygenase 1 Gene

Ido1 - indoleamine 2,3-dioxygenase 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

中文名称：吲哚胺 2 ,3-双加氧酶 1

种属: Mus musculus

同用名: Ido; Indo

基因 ID: 15930 | 基因类型: protein coding

关于 Ido1

Chromosome 8: 25,074,152-25,087,025 reverse strand.GRCm39:CM001001.3

This gene has 2 transcripts (splice variants), 98 orthologues and is associated with 34 phenotypes. Biased expression in genital fat pad adult (RPKM 37.1), mammary gland adult (RPKM 7.7) and 2 other tissues.

功能概要

该基因编码的蛋白可启动色氨酸 2,3-双加氧酶活性。作用于多个过程的上游或内部，包括羧酸代谢过程；细胞凋亡过程的调节；和调节细胞因子的产生。位于平滑肌收缩纤维和静纤毛束中。在大脑皮层表达；纹状体；胚胎;胚外成分；和海马体。用于研究先兆子痫。与人类 IDO1（吲哚胺 2,3-双加氧酶 1）同源。 [由基因组资源联盟提供，2022 年 4 月]

Enables tryptophan 2,3-dioxygenase activity. Acts upstream of or within several processes, including carboxylic acid metabolic process; regulation of apoptotic process; and regulation of cytokine production. Located in smooth muscle contractile fiber and stereocilium bundle. Is expressed in cerebral cortex; corpus striatum; embryo; extraembryonic component; and hippocampus. Used to study pre-eclampsia. Orthologous to human IDO1 (indoleamine 2,3-dioxygenase 1). [provided by Alliance of Genome Resources, Apr 2022]

Ido1 基因产物(2)

mRNA Protein Name
NM_008324.3 NP_032350.1 indoleamine 2,3-dioxygenase 1 isoform 1
NM_001293690.2 NP_001280619.1 indoleamine 2,3-dioxygenase 1 isoform 2

Ido1 蛋白结构

IDO

IDO: pfam01231 (15 - 401)

  • 0
  • 100
  • 200
  • 300
  • 407 a.a.
蛋白主名 其他名称

indoleamine 2,3-dioxygenase 1

IDO-1

indole 2,3-dioxygenase

indoleamine-pyrrole 2,3 dioxygenase

重组 Ido1 蛋白

目录号 产品名 蛋白编号 纯度
HY-P72616 IDO Protein, Mouse (His) P28776 (M1-P407) ≥95%

相关产品

Approval
生物活性分子 (2)
目录号 产品名 作用方式
纯度 是否罕见病
HY-N0110 Palmatine chloride Inhibitor 99.77% 否
HY-N0110A Palmatine Inhibitor / 否
Clinical Phase
生物活性分子 (3)
目录号 产品名 作用方式
纯度 Phase
HY-15689 Epacadostat Inhibitor 99.66% Phase 3
HY-101560 Linrodostat Inhibitor 99.89% Phase 3
HY-101111 PF-06840003 Inhibitor 99.95% Phase 1
Pre-clinical Phase
生物活性分子 (27)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-13983 IDO-IN-7 Inhibitor 99.98% 否
HY-148383 DP00477 Inhibitor 99.03% 否
HY-151108 IDO1/TDO-IN-4 Inhibitor 99.23% 否
HY-111540 LY-3381916 Inhibitor 99.54% 否
HY-131911 PROTAC IDO1 Degrader-1 Inhibitor 98.17% 否
HY-151093 IDO2-IN-1 Inhibitor 98.86% 否
HY-N0110B Palmatine hydroxide Inhibitor 99.64% 否
HY-18769 BMS-978587 Inhibitor 99.92% 否
HY-139204 BMS-986242 Inhibitor 99.42% 否
HY-145280 IDO1/2-IN-1 Inhibitor 98.06% 否
HY-148572 NAMPT/IDO1-IN-1 Inhibitor / 否
HY-151886 NU223612 Inhibitor / 否
HY-149227 IDO1-IN-21 Inhibitor / 否
HY-161348 AT-0174 Inhibitor / 否
HY-120742 MMG-0358 Inhibitor / 否
HY-154387 1-Isopropyltryptophan Inhibitor / 否
HY-144274 IDO1-IN-14 Inhibitor / 否
HY-144466 IDO1-IN-16 Inhibitor / 否
HY-144652 IDO1-IN-19 Inhibitor 98.52% 否
HY-144273 IDO1-IN-13 Inhibitor / 否
HY-147772 ZC0101 Inhibitor / 否
HY-144465 IDO1-IN-15 Inhibitor / 否
HY-D0033 Roxyl-9 Inhibitor 99.22% 否
HY-144778 IDO1/TDO-IN-1 Inhibitor / 否
HY-144468 IDO1-IN-17 Inhibitor / 否
HY-130607 IDO1-IN-2 Inhibitor / 否
HY-112147 IDO1 and HDAC1 Inhibitor Inhibitor / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Ido1 NCBI NCBI:3620
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