Il4 - interleukin 4 Gene

中文名称：白细胞介素 4

种属: Rattus norvegicus

同用名: Il4e12

关于 Il4

功能概要

预测该基因编码的蛋白可启动细胞因子活性。参与多个过程，包括生物合成过程的正向调节；白细胞迁移的正向调节；和防御反应的调节。位于细胞外空间。用于研究抗基底膜肾小球肾炎；自身免疫性甲状腺炎;和盆腔炎。多种疾病的生物标志物，包括脑血管疾病（多种）；间质性肺病（多发性）；刺激性皮炎;原发性胆汁性胆管炎;和鼻炎（多种）。该基因的人类直系同源物与多种疾病有关，包括哮喘（多种）；自身免疫性疾病（多种）；乙型肝炎；丙型肝炎;和胰腺癌（多发）。与人 IL4（白细胞介素 4）同源。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable cytokine activity. Involved in several processes, including positive regulation of biosynthetic process; positive regulation of leukocyte migration; and regulation of defense response. Located in extracellular space. Used to study anti-basement membrane glomerulonephritis; autoimmune thyroiditis; and pelvic inflammatory disease. Biomarker of several diseases, including cerebrovascular disease (multiple); interstitial lung disease (multiple); irritant dermatitis; primary biliary cholangitis; and rhinitis (multiple). Human ortholog(s) of this gene implicated in several diseases, including asthma (multiple); autoimmune disease (multiple); hepatitis B; hepatitis C; and pancreatic Cancer (multiple). Orthologous to human IL4 (interleukin 4). [provided by Alliance of Genome Resources, Apr 2022]