1. Membrane Transporter/Ion Channel Neuronal Signaling
  2. Calcium Channel
  3. Manidipine

Manidipine  (Synonyms: 马尼地平)

目录号: HY-B0419
产品使用指南

Manidipine是钙离子通道阻断剂,有降压作用。

在相同的摩尔浓度下,化合物盐形式与游离形式有相同的生物活性,但盐形式 Manidipine dihydrochloride 通常具有更好的水溶性和稳定性。

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Manidipine Chemical Structure

Manidipine Chemical Structure

CAS No. : 89226-50-6

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Manidipine 的其他形式现货产品:

Other Forms of Manidipine:

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Manidipine is a calcium channel blocker that is used clinically as an antihypertensive. Target: Calcium Channel Manidipine is a dihydropyridine calcium antagonist, which causes systemic vasodilation by inhibiting the voltage-dependent calcium inward currents in smooth muscle cells. Manidipine was well tolerated in clinical trials, with most adverse effects related to vasodilation [1]. Manidipine is a lipophilic, third-generation dihydropyridine calcium channel antagonist with a high degree of selectivity for the vasculature, thereby inducing marked peripheral vasodilation with negligible cardiodepression. manidipine represents a first-line treatment option for patients with essential mild-to-moderate hypertension [2]. Manidipine has neutral effects on glucose and lipid metabolism and is generally well tolerated. Manidipine thus represents a first-line option for lowering BP in patients with mild-to-moderate hypertension [3].

Clinical Trial
分子量

610.70

Formula

C35H38N4O6

CAS 号
中文名称

马尼地平;美尼地平

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Manidipine
目录号:
HY-B0419
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