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N,N-Dipropyldopamine hydrobromide 

目录号: HY-132219 纯度: 98.22%
COA 产品使用指南

N,N-dipropyldopamine 是一种具有抑癌活性的谷氨酸释放 (glutamate release) 的高效抑制剂。谷氨酸释放增加导致癌症引起的骨痛cancer-induced bone pain (CIBP)。N,N-dipropyldopamine 能缓解癌症引起的骨痛。

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N,N-Dipropyldopamine hydrobromide Chemical Structure

N,N-Dipropyldopamine hydrobromide Chemical Structure

CAS No. : 65273-66-7

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Customer Review

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

N. N-dipropyrldopamine is a potent inhibitor of glutamate release and has anticancer activity. The increase of glutamate secretion leads to cancer-induced bone pain (CIBP). N. N-dipropyrldopamine plays an analgesic role in CIBP[1].

IC50 & Target

cystine/glutamate transporter (XC-)[1] IC50:25.45 μM (cystine/glutamate transporter, XC-)[1]

体外研究
(In Vitro)

N,N-dipropyldopamine (10-200 μM, 48 小时) 显著抑制 MDA-MB-231, MCF-7, Mat-Ly-Lu 细胞生长, IC50 分别为 25.45, 26.3, 28.45 μM[1]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Viability Assay[1]

Cell Line: MDA-MB-231, MCF-7 and Mat-Ly-Lu
Concentration: 0-200 μM
Incubation Time: 48 h
Result: Inhibited cell growth with IC50 values of 25.45 μM (MDA-MB-231), 26.3 μM (MCF-7), 28.45 μM (Mat-Ly-Lu).
分子量

318.25

Formula

C14H24BrNO2

CAS 号
性状

固体

颜色

White to light yellow

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

纯度 & 产品资料
参考文献

N,N-Dipropyldopamine hydrobromide 相关分类

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
N,N-Dipropyldopamine hydrobromide
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HY-132219
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