1. Others Cell Cycle/DNA Damage
  2. Isotope-Labeled Compounds CDK
  3. Palbociclib-d4 hydrochloride

Palbociclib-d4 hydrochloride  (Synonyms: PD 0332991-d4 hydrochloride)

目录号: HY-50767S1
产品使用指南 技术支持

Palbociclib-d4 (hydrochloride) 是 Palbociclib hydrochloride 的氘代物。Palbociclib (PD 0332991) hydrochloride 是选择性的 CDK4CDK6 抑制剂,IC50 分别为11 nM,16 nM。Palbociclib 有潜力用于 ER 阳性和 HER2 阴性乳腺癌的研究。

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Palbociclib-d<sub>4</sub> hydrochloride Chemical Structure

Palbociclib-d4 hydrochloride Chemical Structure

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规格 是否有货
1 mg 询价
5 mg 询价

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Customer Review

Other Forms of Palbociclib-d4 hydrochloride:

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Palbociclib-d4 (hydrochloride) is the deuterium labeled Palbociclib hydrochloride. Palbociclib (PD 0332991) is a selective CDK4 and CDK6 inhibitor with IC50s of 11 and 16 nM, respectively. Palbociclib has the potential for ER-positive and HER2-negative breast cancer research[1].

体外研究
(In Vitro)

氢、碳和其他元素的稳定重同位素已被掺入药物分子中,主要用作药物开发过程中定量的示踪剂。氘代因其可能影响药物的药代动力学和代谢特征而受到关注[1]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

488.02

同用名

PD 0332991-d4 hydrochloride

Formula

C24H26D4ClN7O2

非标记 CAS
中文名称

帕布昔利布 d4 (盐酸盐)

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Palbociclib-d4 hydrochloride
目录号:
HY-50767S1
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