2. Cell Cycle/DNA Damage PI3K/Akt/mTOR
  3. ATM/ATR
  4. WSD0628

WSD0628 是可透过血脑屏障的，有效的 ATM 抑制剂，具有明显的放射增敏效果。

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WSD0628 Chemical Structure

WSD0628 Chemical Structure

CAS No. : 2765448-96-0

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2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 是否有货
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WSD0628 相关抗体

Top Publications Citing Use of Products

查看 ATM/ATR 亚型特异性产品:

查看所有亚型
ATM ATR

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

WSD0628 is a brain penetrant and potent ATM inhibitor with profound radiosensitizing effect[1].

体外研究
(In Vitro)

WSD0628 significantly increased the radiosensitivity of U251 cells in clonogenic survival assays (0 nM vs. 30 nM at 5Gy, p<0.01)[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

WSD0628 相关抗体:
体内研究
(In Vivo)

WSD0628 (10 mg/kg, a single dose of 12.5 Gy combined) has profound impact on treatment efficacy in the melanoma brain metastasis M12 PDX[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

439.46

Formula

C23H23F2N5O2
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

WSD0628 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

WSD06282765448-96-0WSD 0628WSD-0628ATM/ATRAtaxia telangiectasia mutatedATM and RAD3 relatedradiosensitivityU251ATMInhibitorinhibitorinhibit

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产品名称：
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目录号：
HY-162002
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