1. GPCR/G Protein Neuronal Signaling
  2. Cannabinoid Receptor
  3. CB1R Allosteric modulator 5

CB1R Allosteric modulator 5 (compound 3) 是一种选择性的、具有血脑屏障通透性的大麻素受体1型 (Cannabinoid receptor type 1) 变构调节剂,其 pIC0 值为 6.89。 CB1R Allosteric modulator 5 在不改变运动活动的情况下减弱线索诱导的可卡因寻求行为恢复和可卡因诱导的行为敏感化。

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CB1R Allosteric modulator 5 Chemical Structure

CB1R Allosteric modulator 5 Chemical Structure

CAS No. : 3019958-44-9

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10 mg ¥1800
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生物活性

CB1R Allosteric modulator 5 (compound 3) is a selective, and blood-brain barrier (BBB) permeable Cannabinoid receptor type 1 allosteric modulator with a pIC50 of 6.89. CB1R Allosteric modulator 5 attenuates both cocaine-seeking behavior specific to cue-induced reinstatement and cocaine-induced behavioral sensitization without altering locomotor activity[1].

分子量

361.22

Formula

C18H14Cl2N2O2

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
CB1R Allosteric modulator 5
目录号:
HY-172587
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