1. Cell Cycle/DNA Damage
  2. CDK
  3. CDK2-IN-22

CDK2-IN-22 (compound 7I) 是一种有效的 CDK2 抑制剂,IC50 为 64.42 nM。CDK2-IN-22 对多种癌细胞 MV4-11、HT-29、MCF-7 和 HeLa 表现出广泛的抗增殖功效,IC50 值分别为 0.83 μM、2.12 μM、3.12 μM 和 8.61 μM。

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CDK2-IN-22 Chemical Structure

CDK2-IN-22 Chemical Structure

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Customer Review

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

CDK2-IN-22 (compound 7I) is a potent CDK2 inhibitor with an IC50 of 64.42 nM. CDK2-IN-22 presents a broad antiproliferative efficacy toward diverse cancer cells MV4-11, HT-29, MCF-7, and HeLa with IC50 values of 0.83 μM, 2.12 μM, 3.12 μM, and 8.61 μM, respectively[1].

IC50 & Target[1]

CDK2

64.42 nM (IC50)

分子量

434.47

Formula

C21H18N6O3S

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

CDK2-IN-22 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
CDK2-IN-22
目录号:
HY-157516
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