1. Metabolic Enzyme/Protease
  2. MMP
  3. DB04760

DB04760 

目录号: HY-125166
产品使用指南

DB04760 (compound 4) 是一种有效的,高选择性,非锌螯合的 MMP-13 抑制剂,IC50 为 8 nM。DB04760 显着降低紫杉醇的神经毒性并具有抗癌活性。

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DB04760 Chemical Structure

DB04760 Chemical Structure

CAS No. : 544678-85-5

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Description

DB04760 (compound 4) is a potent, highly selective, non-zinc-chelating MMP-13 inhibitor with an IC50 of 8 nM[1]. DB04760 significantly reduces paclitaxel neurotoxicity and has anticancer activity[2].

IC50 & Target[1]

MMP-13

8 nM (IC50)

Molecular Weight

410.42

Formula

C₂₂H₂₀F₂N₄O₂

CAS No.

544678-85-5

SMILES

FC1=C(C=C(C=C1)CNC(C2=CC(C(NCC3=CC=C(C(C)=C3)F)=O)=NC=N2)=O)C

Shipping

Room temperature in continental US; may vary elsewhere

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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Inquiry Information

产品名称:
DB04760
目录号:
HY-125166
需求量:

DB04760

Cat. No.: HY-125166