1. Cell Cycle/DNA Damage
    Protein Tyrosine Kinase/RTK
  2. Haspin Kinase
    DYRK
  3. LDN-192960 hydrochloride

LDN-192960 hydrochloride 

目录号: HY-13455A
产品使用指南

LDN-192960 hydrochloride 是 HaspinDYRK2 的双重抑制剂,IC50 值分别为 10 nM 和 48 nM。

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LDN-192960 hydrochloride Chemical Structure

LDN-192960 hydrochloride Chemical Structure

CAS No. : 2309172-48-1

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Description

LDN-192960 hydrochloride is a dual inhibitor of Haspin and DYRK2 with IC50s of 10 nM and 48 nM, respectively[1].

IC50 & Target

IC50: 0.21 μM (CLK1); 0.10 μM (DYRK1A); 2 nM (DYRK2); 19 nM (DYRK3); 1.6 μM (ROS); 1.4 μM (HIPK1); 1.3 μM (HIPK2); 0.72 μM (PIM1); 56 μM (PIM2)[1]

Molecular Weight

401.35

Formula

C₁₈H₂₂Cl₂N₂O₂S

CAS No.

2309172-48-1

SMILES

NCCCSC1=C(C=C(OC)C=C2)C2=NC3=CC=C(OC)C=C31.Cl.Cl

Shipping

Room temperature in continental US; may vary elsewhere

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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产品名称:
LDN-192960 hydrochloride
目录号:
HY-13455A
需求量:

LDN-192960 hydrochloride

Cat. No.: HY-13455A