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Polythiazide  (Synonyms: 多噻嗪；泊利噻嗪；三氟硫醚甲噻嗪；聚噻嗪)

目录号: HY-16403 纯度: 98.22%
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Polythiazide 是一种有效的、具有口服活性的噻嗪类利尿剂，具有抗高血压作用。Polythiazide 可减轻水肿和降血压。Polythiazide 还具有光毒性。

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Polythiazide Chemical Structure

Polythiazide Chemical Structure

CAS No. : 346-18-9

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1 mg ￥1480
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10 mg ￥6630
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Polythiazide 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Polythiazide is a potent and orally active thiazide diuretic agent that has antihypertensive effect. Polythiazide can decrease edema and decrease blood pressure. Polythiazide also has phototoxicity[1][2][3].

体外研究
(In Vitro)

Polythiazide (500 μM, 1 min) induces significant phototoxic NHIK 3025 cell death under Bluelight 2000 apparatus (Ex: 325 nM)[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Polythiazide 相关抗体:
体内研究
(In Vivo)

Polythiazide (oral gavage, 10 mg/kg, daily for 5 days) Increases plasma cholesterol levels in Cholesterol-fed C57BL/cdJ mouse[3].
Polythiazide (oral administration, 0.4 mg/kg) shows diuretic and saluretic effects in hypertensive dogs and rats[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Cholesterol-fed C57BL/cdJ mice[3]
Dosage: 10 mg/kg
Administration: Oral gavage, daily for 5 days
Result: Caused approximately 13% rise in total plasma cholesterol levels, and increased non-HDL lipoprotein fraction.
Animal Model: Hypertensive dogs[1]
Dosage: 0.4 mg/kg
Administration: Oral administration, daily for 5 days
Result: Increased in excretion of sodium and chloride.
Animal Model: Hypertensive rats[1]
Dosage: 0.05, 0.1, 0.2, 0.4 mg/kg
Administration: Oral administration, twice a day for 3 days.
Result: Displayed natriuretic and chloruretic effects.
分子量

439.88

Formula

C11H13ClF3N3O4S3
CAS 号
性状

固体

颜色

White to off-white

中文名称

多噻嗪；泊利噻嗪；三氟硫醚甲噻嗪；聚噻嗪
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
纯度 & 产品资料
参考文献

Polythiazide 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Polythiazide346-18-9多噻嗪泊利噻嗪三氟硫醚甲噻嗪聚噻嗪OthersHypertensionedemaphototoxicNHIK 3025cholesterollipoproteinantihypertensiveInhibitorinhibitorinhibit

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