1. Immunology/Inflammation
  2. Toll-like Receptor (TLR)
  3. MMG-11

MMG-11 

目录号: HY-112146
产品使用指南

MMG-11 是一种有效的选择性人 TLR2 拮抗剂。MMG-11 抑制 TLR2/1 和 TLR2/6 信号转导,抑制 Pam3CSK4 诱导的 hTLR2/1,IC50 为 1.7 μM,抑制 Pam2CSK4 诱导的 hTLR2/6 反应,IC50 为 5.7 μM。

MCE 的所有产品仅用作科学研究,我们不为任何个人用途提供产品和服务

MMG-11 Chemical Structure

MMG-11 Chemical Structure

CAS No. : 313254-94-3

1.  客户无需承担相应的运输费用。

2.  同一机构(单位)同一产品试用装仅限申领一次,同一机构(单位)一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户

Size Price Stock
10 mg ¥3100 Ask For Quote & Lead Time
50 mg ¥9950 Ask For Quote & Lead Time
100 mg ¥16500 Ask For Quote & Lead Time

* Please select Quantity before adding items.

MMG-11 的其他形式现货产品:

Customer Review

Other Forms of MMG-11:

Top Publications Citing Use of Products
  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

Description

MMG-11 is a potent and selective human TLR2 antagonist with low cytotoxicity. MMG-11 inhibits both TLR2/1 and TLR2/6 signaling with IC50s of 1.7 µM for Pam3CSK4-induced hTLR2/1 and 5.7 µM for Pam2CSK4-induced hTLR2/6 responses[1].

IC50 & Target[1]

TLR2

 

In Vitro

MMG-11 neither shows cellular toxicity nor interference with signaling induced by other TLR agonists, IL-1β or TNF. MMG-11 (0.01-100 µM) shows no cytotoxic effects up to 100 µM in peripheral blood mononuclear cells (PBMCs)[1].

Cell Cytotoxicity Assay[1]

Cell Line: PBMCs
Concentration: 0.01, 1, 10, 100 µM
Incubation Time:
Result: Showed no cytotoxic effects up to 100 µM.
Molecular Weight

306.27

Formula

C₁₅H₁₄O₇

CAS No.

313254-94-3

SMILES

OC1=C(O)C(O)=C(C(CC2=CC=C(C(OCC)=O)O2)=O)C=C1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

MMG-11MMG11MMG 11Toll-like Receptor (TLR)Inhibitorinhibitorinhibit

您最近查看的产品:

Your information is safe with us. * Required Fields.

   产品名称:

 

* 需求量:

* 客户姓名:

 

* Email:

* 电话:

 

* 公司或机构名称:

   留言给我们:

Bulk Inquiry

Inquiry Information

产品名称:
MMG-11
目录号:
HY-112146
需求量: