1. Immunology/Inflammation Protein Tyrosine Kinase/RTK PI3K/Akt/mTOR Stem Cell/Wnt MAPK/ERK Pathway Metabolic Enzyme/Protease
  2. Interleukin Related FAK Src Akt ERK MMP
  3. IL13Rα2 D1

IL13Rα2 D1 是一种有效的 IL-13/IL13Rα2 信号轴抑制剂。IL13Rα2 D1 可以抑制 IL-13 诱导的细胞粘附、迁移、侵袭和增殖。IL13Rα2 D1 可以抑制 FAK、Src、AKT、ERK1/2 磷酸化和 MMP 表达。IL13Rα2 D1 可以用于癌症如结直肠癌的研究。

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IL13Rα2 D1

IL13Rα2 D1 Chemical Structure

CAS No. : 2319573-67-4

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Customer Review

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

IL13Rα2 D1 is an effective IL-13/IL13Rα2 signaling axis inhibitor. IL13Rα2 D1 can inhibit IL-13-induced cell adhesion, migration, invasion, and proliferation. IL13Rα2 D1 can inhibit FAK, Src, AKT, ERK1/2 phosphorylation, and MMP expression. IL13Rα2 D1 can be used for research on cancers such as colorectal cancer[1].

IC50 & Target[1]

IL-13

 

分子量

1377.54

Formula

C61H100N16O20

CAS 号
Sequence

Gly-Ser-Glu-Thr-Trp-Lys-Thr-Ile-Ile-Thr-Lys-Asn

Sequence Shortening

GSETWKTIITKN

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
IL13Rα2 D1
目录号:
HY-P11147
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