1. Metabolic Enzyme/Protease
  2. Glutaminase
  3. IPN-60090 dihydrochloride

IPN-60090 dihydrochloride 

目录号: HY-103671A
产品使用指南

IPN-60090 dihydrochloride 是一种口服有效、选择性的肾脏型谷氨酰胺酶 GLS1 抑制剂。GLS1 是代谢能生产中一种重要的酶。IPN-60090 dihydrochloride 可以用于 GLS1 介导的疾病的研究。

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IPN-60090 dihydrochloride Chemical Structure

IPN-60090 dihydrochloride Chemical Structure

CAS No. : 2102101-72-2

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Size Price Stock
5 mg ¥5800 Ask For Quote & Lead Time
10 mg ¥9800 Ask For Quote & Lead Time
25 mg ¥19000 Ask For Quote & Lead Time
50 mg ¥32000 Ask For Quote & Lead Time
100 mg ¥50000 Ask For Quote & Lead Time

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Description

IPN-60090 dihydrochloride is an orally bioavailable and selective inhibitor of GLS1 (the kidney-type glutaminase), an important enzyme for metabolic energy production. IPN-60090 dihydrochloride can be used in the research of GLS1-mediated diseases[1][2].

IC50 & Target

GLS1[1]

In Vitro

IPN-60090 dihydrochloride (Example 1) has an IC50 against GLS1 and an EC50 against A549 cell proliferation of <100 nM[2].

Molecular Weight

605.44

Formula

C₂₄H₂₉Cl₂F₃N₈O₃

CAS No.

2102101-72-2

SMILES

O=C(NC)C1=CN(C[C@H](F)CCC2=NN=C(NC(CC3=NC(C)=CC(OC4CC(F)(F)C4)=C3)=O)C=C2)N=N1.[H]Cl.[H]Cl

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

IPN-60090IPN60090IPN 60090Glutaminasekidney-typeglutaminaseGLS1cancerimmunologicalneurologicaldisordersInhibitorinhibitorinhibit

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产品名称:
IPN-60090 dihydrochloride
目录号:
HY-103671A
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