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  3. Lanreotide

Lanreotide  (Synonyms: BIM 23014)

目录号: HY-P1959
产品使用指南

摩尔计算器

Lanreotide (BIM 23014) 是一种具有抗肿瘤活性的生长抑素类似物。Lanreotide 可用于类癌综合症的研究。

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Custom Peptide Synthesis

Lanreotide Chemical Structure

Lanreotide Chemical Structure

CAS No. : 108736-35-2

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Lanreotide 的其他形式现货产品:

Customer Review

Other Forms of Lanreotide:

Lanreotide 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Lanreotide (BIM 23014) is a somatostatin analogue with antineoplastic activity. Lanreotide can be used for the research of carcinoid syndrome[1][2].

体外研究
(In Vitro)

Lanreotide (BIM 23014) (100  nM; 0-48 h) enhanced radiation-induced apoptosis[1].
Lanreotide results in a dose-dependent decrease in GH3 cell colony forming units. Lanreotide at concentrations of 1, 10, 100, and 1000 nM results in cell survival rates of 75, 56, 39 and 27% respectively. The IC50 is 57 nM[1].
Lanreotide inhibits GH-secreting pituitary adenoma cell proliferation and hormone release in vitro[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Lanreotide 相关抗体:

Apoptosis Analysis[1]

Cell Line: GH3
Concentration: 100 nM
Incubation Time: 48 h, 24 h, or immediately (0 h) before radiation
Result: Increased apoptotic sub-G1 proportion compared with radiation alone.
体内研究
(In Vivo)

Lanreotide (2.5-10mg/kg; s.c.; daily for 5 days) results in tumor growth inhibition[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Male nude mice, 8 weeks old and 20–25 g in body weight (GH3 tumor-bearing nude mice)[1]
Dosage: 2.5, 5, 10 mg/kg
Administration: Subcutaneous; daily for 5 days
Result: Produced tumor growth inhibition.
Clinical Trial
分子量

1096.32

Formula

C54H69N11O10S2
CAS 号
Sequence Shortening

{d-2nal}-CY-{d-Trp}-KVCT-NH2 (Disulfide bridge: Cys2-Cys7)
中文名称

兰瑞肽
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Lanreotide108736-35-2BIM 23014兰瑞肽BIM23014BIM-23014OtherstumorGH-secretingpituitaryadenomahormoneapoptosisGH3 cellInhibitorinhibitorinhibit

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