2. Metabolic Enzyme/Protease Immunology/Inflammation GPCR/G Protein Neuronal Signaling
  3. Endogenous Metabolite Histamine Receptor
  4. Olopatadine

Olopatadine 是一种具有口服活性和选择性的组胺 1 (H1) 受体拮抗剂，也是肥大细胞稳定剂。Olopatadine 可以防止人结膜肥大细胞释放免疫刺激的促炎介质。Olopatadine 可用于过敏性结膜炎的研究。

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Olopatadine Chemical Structure

Olopatadine Chemical Structure

CAS No. : 113806-05-6

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规格 价格 是否有货
5 mg ￥1440
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Olopatadine 的其他形式现货产品:

Customer Review

Other Forms of Olopatadine:

Olopatadine 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Olopatadine is an orally active and selective histamine 1 (H1) receptor antagonist and a mast cell stabilizer. Olopatadine prevents immunologically stimulated pro-inflammatory mediator release from human conjunctival mast cells. Olopatadine can be used for researching allergic conjunctivitis[1][2].

IC50 & Target[1]

H1 Receptor

 

体外研究
(In Vitro)

Olopatadine inhibits anti-IgE antibody-mediated release of TNF-α from human conjunctival mast cells, and significantly decreases the mast cell supernatant-mediated upregulation of ICAM (intercellular adhesion molecule)-1 on human conjunctival epithelial cells in vitro[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Olopatadine 相关抗体:
Clinical Trial
分子量

337.41

Formula

C21H23NO3
CAS 号
结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Olopatadine 相关分类

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Olopatadine113806-05-6Endogenous MetaboliteHistamine ReceptorH1mast cellallergicconjunctivitispro-inflammatoryTNF-αorally activeInhibitorinhibitorinhibit

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