2. GPCR/G Protein
  3. Adenosine Receptor
  4. A2AAR antagonist 2

3′-Methoxyfurano[4″,5″:3,4]chalcone (化合物 2) 是一种选择性 A2AAR 拮抗剂 (IC50=33.5 nM)，具有高亲和力。3′-Methoxyfurano[4″,5″:3,4]chalcone 也是一种天然产物，可从 Allium cepa L. 皮中获得。3′-Methoxyfurano[4″,5″:3,4]chalcone 能以促进 T 细胞活化，可用癌症免疫研究。

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A2AAR antagonist 2 Chemical Structure

A2AAR antagonist 2 Chemical Structure

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A2AAR antagonist 2 相关抗体

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查看 Adenosine Receptor 亚型特异性产品:

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Adenosine A1 receptor (A1R) Adenosine A2A receptor (A2AR) Adenosine A2B receptor (A2BR) Adenosine A3 receptor (A3R)

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

3′-Methoxyfurano[4″,5″:3,4]chalcone (compound 2) is a selective A2AAR antagonist (IC50=33.5 nM) with high affinity. 3′-Methoxyfurano[4″,5″:3,4]chalcone is also a natural product obtained from the bark of Allium cepa L. 3′-Methoxyfurano[4″,5″:3,4]chalcone can promote T cell activation and can be used in cancer immunity research[1].

IC50 & Target[1]

A2a adenosine receptor

33.5 nM (IC50)

分子量

278.30

Formula

C18H14O3
结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

A2AAR antagonist 2 相关分类

  • 摩尔计算器

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

A2AAR antagonist 2Adenosine ReceptorP1 receptorAllium cepa L.cancerinflammationT cellnatural productInhibitorinhibitorinhibit

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