1. GPCR/G Protein
    Immunology/Inflammation
  2. CCR
  3. ML604086

ML604086 

目录号: HY-124416
产品使用指南

ML604086 是一种选择性的 CCR8 抑制剂,抑制循环T细胞上 CCL1 与 CCR8 结合。ML604086 抑制 CCL1 介导的趋化作用,增加细胞内 Ca2+浓度。

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ML604086 Chemical Structure

ML604086 Chemical Structure

CAS No. : 850330-18-6

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Description

ML604086 is a selective CCR8 inhibitor, inhibiting CCL1 binding to CCR8 on circulating T-cells. ML604086 inhibits CCL1 mediated chemotaxis and increases in intracellular Ca2+ concentrations[1][2].

IC50 & Target

CCR8[1][2].

Molecular Weight

508.63

Formula

C₂₇H₃₂N₄O₄S

CAS No.

850330-18-6

SMILES

O=C(NC1=C2C=CC=CC2=C(S(=O)(N[C@H]3[C@H](C)CN(C([C@@H](N)C)=O)CC3)=O)C=C1)C4=CC=CC=C4C

Shipping

Room temperature in continental US; may vary elsewhere

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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产品名称:
ML604086
目录号:
HY-124416
需求量:

ML604086

Cat. No.: HY-124416