2. GPCR/G Protein Neuronal Signaling
  3. 5-HT Receptor Adrenergic Receptor
  4. Viloxazine

Viloxazine  (Synonyms: Viloxazin; Emovit)

目录号: HY-W380450
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摩尔计算器

Viloxazine (Viloxazin) 是一种去甲肾上腺素重摄取 (norepinephrine reuptake) 抑制剂，也是有效的 5-HT2C 激动剂和 5-HT2B 拮抗剂，对 5-HT2C 的 EC50 为 32 μM，对 5-HT2B 的 IC50 为 27 μM。Viloxazine 的作用机制主要涉及血清素能和去甲肾上腺素能通路。Viloxazine 可用于抗抑郁研究。

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Viloxazine Chemical Structure

Viloxazine Chemical Structure

CAS No. : 46817-91-8

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Viloxazine 的其他形式现货产品:

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Viloxazine 相关抗体

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  • 生物活性

  • 纯度 & 产品资料

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生物活性

Viloxazine (Viloxazin) is a norepinephrine reuptake inhibitor, also a potent 5-HT2C agonist and 5-HT2B antagonist with an EC50 of 32 μM and an IC50 of 27 μM for 5-HT2C and 5-HT2B, respectively. The mechanism of action of Viloxazine predominantly involves serotonergic and noradrenergic pathways. Viloxazine can be used for researching depression[1][2].

IC50 & Target[1]

Human 5-HT2C Receptor

32 μM (EC50)

human 5-HT2B Receptor

27 μM (IC50)

分子量

237.29

Formula

C13H19NO3
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Viloxazine 相关分类

  • 摩尔计算器

  • 稀释计算器

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Viloxazine46817-91-8Viloxazin Emovit5-HT ReceptorAdrenergic ReceptorSerotonin Receptor5-hydroxytryptamine ReceptorBeta ReceptorSerotonergicnoradrenergic5-HTdepressionInhibitorinhibitorinhibit

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