2. GPCR/G Protein Neuronal Signaling
  3. Adenosine Receptor Monoamine Oxidase
  4. (E)-8-(3-Chlorostyryl)caffeine

(E)-8-(3-Chlorostyryl)caffeine 

目录号: HY-103164
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摩尔计算器

(E)-8-(3-Chlorostyryl)caffeine 是一种选择性腺苷 A2A 受体拮抗剂。(E)-8-(3-Chlorostyryl)caffeine 通过独立于其对 A2A 受体作用的途径抑制单胺氧化酶 B (MAO-B)，Ki 值为 70 nM。(E)-8-(3-Chlorostyryl)caffeine 具有用于帕金森病研究的潜力。

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(E)-8-(3-Chlorostyryl)caffeine Chemical Structure

(E)-8-(3-Chlorostyryl)caffeine Chemical Structure

CAS No. : 147700-11-6

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规格 价格 是否有货 数量
5 mg ￥1672
3 - 4 周
10 mg ￥2678
3 - 4 周
50 mg   询价  
100 mg   询价  

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(E)-8-(3-Chlorostyryl)caffeine 相关抗体

Top Publications Citing Use of Products

查看 Adenosine Receptor 亚型特异性产品:

查看所有亚型
Adenosine A1 receptor (A1R) Adenosine A2A receptor (A2AR) Adenosine A2B receptor (A2BR) Adenosine A3 receptor (A3R)

查看 Monoamine Oxidase 亚型特异性产品:

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MAO-A MAO-B

  • 生物活性

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  • 参考文献

生物活性

(E)-8-(3-Chlorostyryl)caffeine is a selective adenosine A2A receptor antagonist. (E)-8-(3-Chlorostyryl)caffeine inhibits monoamine oxidase B (MAO-B) with a Ki value of 70 nM by a pathway that is independent of its actions on the A2A receptor. (E)-8-(3-Chlorostyryl)caffeine has the potential for Parkinson's disease research[1].

IC50 & Target[1]

A2AR

 

MAO-B

70 nM (Ki)

分子量

330.77

Formula

C16H15ClN4O2
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

(E)-8-(3-Chlorostyryl)caffeine 相关分类

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

(E)-8-(3-Chlorostyryl)caffeine147700-11-6Adenosine ReceptorMonoamine OxidaseP1 receptorMAOadenosine A2A receptormonoamine oxidase BMAO-B,?Parkinson's diseaseInhibitorinhibitorinhibit

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