1. GPCR/G Protein
    Neuronal Signaling
  2. Adrenergic Receptor
  3. (S)-(-)-Propranolol hydrochloride

(S)-(-)-Propranolol hydrochloride 

目录号: HY-B0573A
产品使用指南

(S)-(-)-Propranolol hydrochloride 是一种肾上腺素能受体 (β-adrenergic receptor) 拮抗剂,针对 β1,β2,和β3的 log Kd 值分别为 -8.16,-9.08 和 -6.93。(S)-(-)-Propranolol hydrochloride 可以用于高血压,嗜铬细胞瘤,心肌梗塞,心律不齐,心绞痛和肥大心肌病的相关研究。

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(S)-(-)-Propranolol hydrochloride Chemical Structure

(S)-(-)-Propranolol hydrochloride Chemical Structure

CAS No. : 4199-10-4

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Description

(S)-(-)-Propranolol hydrochloride is a β-adrenergic receptor antagonist with log Kd values of -8.16, -9.08, and -6.93 for β1, β2, and β3, respectively. (S)-(-)-Propranolol hydrochloride the active enantiomer of propranolol and can be s used for study of hypertension, pheochromocytoma, myocardial infarction, cardiac arrhythmias, angina pectoris, and hypertrophic cardiomyopathy[2].

IC50 & Target

log Kd: -8.16 (β1-adrenergic receptor)
log Kd: -9.08 (β2-adrenergic receptor)
log Kd: -6.93 (β3-adrenergic receptor)[1]

Molecular Weight

295.80

Formula

C₁₆H₂₂ClNO₂

CAS No.

4199-10-4

SMILES

O[C@H](COC1=C2C=CC=CC2=CC=C1)CNC(C)C.[H]Cl

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
References
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

(S)-(-)-PropranololAdrenergic ReceptorBeta Receptorhypertensionpheochromocytomamyocardial infarctioncardiac arrhythmiasangina pectoris hypertrophic cardiomyopathyInhibitorinhibitorinhibit

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产品名称:
(S)-(-)-Propranolol hydrochloride
目录号:
HY-B0573A
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