2. Epigenetics
  3. Histone Methyltransferase
  4. EPZ011989 hydrochloride

EPZ011989 hydrochloride 

目录号: HY-16986B 纯度: 99.40%
COA 产品使用指南

摩尔计算器

EPZ011989 hydrochloride 是具有口服活性的EZH2抑制剂，Ki 值为 <3 nM。EPZ011989 具有抗肿瘤活性。EPZ011989 是个点击化学试剂，含有一个炔基，可以与含有叠氮化物基团的分子进行铜催化叠氮化物-炔环加成(CuAAc)。

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EPZ011989 hydrochloride Chemical Structure

EPZ011989 hydrochloride Chemical Structure

CAS No. : 2095432-26-9

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规格 价格 是否有货 数量
5 mg ￥1120
In-stock
10 mg ￥1960
In-stock
25 mg ￥4035
In-stock
50 mg ￥6860
In-stock
100 mg   询价  
200 mg   询价  

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Customer Review

Other Forms of EPZ011989 hydrochloride:

EPZ011989 hydrochloride 相关抗体

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查看 Histone Methyltransferase 亚型特异性产品:

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EZH1 EZH2 DOT1L SMYD2 SMYD3 SUV39H2/KMT1B EHMT2/G9a/KMT1C EHMT1/GLP/KMT1D SETDB1/KMT2G SETD2/KMT3A SETD7/KMT7 SETD8/KMT5A PRMT1 PRMT3 PRMT4 PRMT5 PRMT6 PRMT7 PRMT8

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

EPZ011989 hydrochloride is a potent and orally active Zeste Homolog 2 (EZH2) inhibitor, with a Ki value of <3 nM. EPZ011989 shows anti-tumor activity. EPZ011989 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups[1].

分子量

642.27

性状

固体

Formula

C35H52ClN5O4
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

4°C, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)

纯度 & 产品资料
参考文献

EPZ011989 hydrochloride 相关分类

  • 摩尔计算器

  • 稀释计算器

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

EPZ0119892095432-26-9EPZ 011989EPZ-011989Histone MethyltransferaseEZH2anti-tumorCuAAcInhibitorinhibitorinhibit

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