2. GPCR/G Protein Neuronal Signaling
  3. 5-HT Receptor
  4. GR127935

GR127935 是一种有效且具有口服活性的 5-HT1D 和 5-HT1B 受体拮抗剂，pKi 值均为 8.5。GR127935 对 5-HT1B/1D 受体的选择性是 5-HT1A、5-HT2A 和 5-HT2C 受体的 100 倍。GR127935 可用于神经疾病研究。

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GR127935

GR127935 Chemical Structure

CAS No. : 148672-13-3

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规格 价格 是否有货
1 mg ￥700
询问价格 & 货期
5 mg ￥1430
询问价格 & 货期
10 mg ￥2300
询问价格 & 货期

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GR127935 的其他形式现货产品:

Customer Review

Other Forms of GR127935:

GR127935 相关抗体

Top Publications Citing Use of Products

查看 5-HT Receptor 亚型特异性产品:

查看所有亚型
5-HT Receptor 5-HT1 Receptor 5-HT2 Receptor 5-HT3 Receptor 5-HT4 Receptor 5-HT5 Receptor 5-HT6 Receptor 5-HT7 Receptor

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

GR127935 is a potent and orally active 5-HT1D and 5-HT1B receptor antagonist with pKis of 8.5 for both isoforms. GR127935 hydrochloride has 100-fold selectivity for 5-HT1B/1D receptors over 5-HT1A, 5-HT2A, and 5-HT2C receptors. GR127935 can be used in neurological disease research[1][2].

IC50 & Target

5-HT1D Receptor

 

分子量

497.59

Formula

C29H31N5O3
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

GR127935 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

GR127935148672-13-3GR 127935GR-1279355-HT ReceptorSerotonin Receptor5-hydroxytryptamine Receptor5-HT1D5-HT1B receptorneurological diseaseorally activeInhibitorinhibitorinhibit

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产品名称：
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目录号：
HY-123869
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