1. GPCR/G Protein
    Neuronal Signaling
    Metabolic Enzyme/Protease
    Others
  2. Cannabinoid Receptor
    Fatty Acid Synthase (FAS)
    Androgen Receptor
  3. Leelamine hydrochloride

Leelamine hydrochloride 

目录号: HY-110028
产品使用指南

Leelamine hydrochloride 是一种从松树皮中提取的三环二萜分子。Leelamine hydrochloride 是一种大麻素 1 型 (CB1) 激动剂,也是前列腺癌细胞中 SREBP1 调节的脂肪酸/脂质合成的抑制剂,不受雄激素受体状态的影响。Leelamine hydrochloride 抑制调节脂肪酸合成的雄激素受体 (androgen receptor) 的转录活性。

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Leelamine hydrochloride Chemical Structure

Leelamine hydrochloride Chemical Structure

CAS No. : 16496-99-4

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Description

Leelamine hydrochloride is a tricyclic diterpene molecule that is extracted from the bark of pine trees[1]. Leelamine hydrochloride is a cannabinoid receptor type 1 (CB1) agonist and a inhibitor of SREBP1-regulated fatty acid/lipid synthesis in prostate cancer cells that is not affected by androgen receptor status. Leelamine hydrochloride suppresses transcriptional activity of androgen receptor, which is known to regulate fatty acid synthesis[2,3].

IC50 & Target

CB1

 

Molecular Weight

321.93

Formula

C₂₀H₃₂ClN

CAS No.

16496-99-4

SMILES

NC[C@]1(C)CCC[C@]2(C)C3=C(CC[C@@]12[H])C=C(C(C)C)C=C3.Cl

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

LeelamineCannabinoid ReceptorFatty Acid Synthase (FAS)Androgen ReceptorInhibitorinhibitorinhibit

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产品名称:
Leelamine hydrochloride
目录号:
HY-110028
需求量: