1. Protein Tyrosine Kinase/RTK
  2. VEGFR
  3. AG-13958

AG-13958 (Synonyms: AG-013958)

目录号: HY-15492
产品使用指南

AG-13958 (AG-013958) 是一种有效的 VEGFR 酪氨酸激酶抑制剂,用于治疗年龄相关性黄斑变性 (AMD) 的脉络膜新生血管形成。

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AG-13958 Chemical Structure

AG-13958 Chemical Structure

CAS No. : 319460-94-1

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Size Price Stock Quantity
10 mM * 1 mL in DMSO ¥4675 In-stock
5 mg ¥4250 In-stock
10 mg ¥7200 In-stock
50 mg ¥22000 In-stock
100 mg ¥37000 In-stock
200 mg   Get quote  
500 mg   Get quote  

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Description

AG-13958 (AG-013958), a potent VEGFR tyrosine kinase inhibitor, is used for treatment of choroidal neovascularization associated with age-related macular degeneration (AMD)[1].

IC50 & Target[1]

VEGFR

 

Molecular Weight

467.50

Formula

C₂₆H₂₂FN₇O

CAS No.

319460-94-1

SMILES

O=C(C1=CC(C)=NN1C)NC2=CC(NC3=CC4=C(C=C3)C(/C=C/C5=NC=CC=C5)=NN4)=CC=C2F

Shipping

Room temperature in continental US; may vary elsewhere

Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 5 mg/mL (10.70 mM; ultrasonic and warming and heat to 60°C)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.1390 mL 10.6952 mL 21.3904 mL
5 mM 0.4278 mL 2.1390 mL 4.2781 mL
10 mM 0.2139 mL 1.0695 mL 2.1390 mL
* 请根据产品在不同溶剂中的溶解度,选择合适的溶剂配制储备液,并请注意储备液的保存方式和期限。
References
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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产品名称:
AG-13958
目录号:
HY-15492
需求量:

AG-13958

Cat. No.: HY-15492