C-Reactive Protein (CRP) (174-185) 

C-Reactive Protein (CRP) is an anti-pneumococcal plasma protein that can serve as an inflammatory marker. C-Reactive protein can protect mice from pneumococcal infection by activating complement. C-Reactive protein can inhibit the activation of caspase-3/9 through the CD64/AKT/mTOR pathway, thereby promoting chemotherapy resistance in mice with tongue squamous cell carcinoma^[1][5].

C-Reactive Protein (CRP) (0-25 μg/mL; 24 h) 通过刺激 3T3-L1 脂肪细胞产生 CXCL7 来促进单核细胞迁移^[3]。
C-Reactive Protein (CRP) 可以损害 G1/S 依赖性肾小管上皮细胞再生^[4]。
C-Reactive Protein (CRP) (10 μg/mL, 4 天) 可以提高 TSCC 细胞活力并增加细胞对 DDP 的耐药性^[5]。
C-Reactive Protein (CRP) 是一种在结构上高度保守的人类主要急性期血浆蛋白^[6]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

C-Reactive Protein (CRP) (25 μg; 每天 1 次; 7 天; 静脉注射) 可以通过激活补体保护小鼠免受肺炎球菌感染^[1]。
C-Reactive Protein (CRP) (20 mg/kg; 每天 1 次; 3 天; 腹腔注射) 可以诱导大鼠巨噬细胞中的超氧阴离子释放和组织因子活性^[2]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

1276.48

C₆₂H₉₃N₁₃O₁₆

147516-85-6

固体

White to off-white

Ile-Tyr-Leu-Gly-Gly-Pro-Phe-Ser-Pro-Asn-Val-Leu

IYLGGPFSPNVL

Room temperature in continental US; may vary elsewhere.

Sealed storage, away from moisture and light, under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen)

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen)。-80°C储存时，请在6个月内使用，-20°C储存时，请在1个月内使用。

* 备注：如您选择水作为储备液，请稀释至工作液后，再用 0.22 μm 的滤膜过滤除菌后使用。

• [1]. Singh SK, et al. Complement Activation by C-Reactive Protein Is Critical for Protection of Mice Against Pneumococcal Infection. Front Immunol. 2020 Aug 13;11:1812.  [Content Brief]

  [2]. Devaraj S, et al. C-reactive protein stimulates superoxide anion release and tissue factor activity in vivo. Atherosclerosis. 2009 Mar;203(1):67-74.  [Content Brief]

  [3]. Chen JY, et al. C-reactive protein derived from perivascular adipose tissue accelerates injury-induced neointimal hyperplasia. J Transl Med. 2020 Feb 11;18(1):68.  [Content Brief]

  [4]. Tang Y, et al. C-reactive protein promotes acute kidney injury by impairing G1/S-dependent tubular epithelium cell regeneration. Clin Sci (Lond). 2014 May;126(9):645-59.  [Content Brief]

  [5]. Yan X, et al. C-reactive protein promotes tongue squamous cell carcinoma chemoresistance by inhibiting the activation of caspase-3/9 via the CD64/AKT/mTOR pathway. Hum Cell. 2021 Sep;34(5):1424-1433.  [Content Brief]

  [6]. Ansar W, et al. C-reactive protein and the biology of disease. Immunol Res. 2013 May;56(1):131-42.  [Content Brief]