1. Cell Cycle/DNA Damage
  2. CDK
  3. PNU112455A hydrochloride

PNU112455A hydrochloride 

目录号: HY-112468
产品使用指南

PNU112455A hydrochloride 是一种 ATP 竞争性的 CDK2/CDK5 抑制剂。PNU112455A hydrochloride 结合 CDK2/CDK5 ATP 结合位点的 Km 值为 3.6 和 3.2 μM。

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PNU112455A hydrochloride Chemical Structure

PNU112455A hydrochloride Chemical Structure

CAS No. : 21886-12-4

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Description

PNU112455A hydrochloride is an ATP-competitive CDK2 and CDK5 inhibitor. PNU112455A hydrochloride binds to the ATP site of CDK2 and CDK5 with Kms of 3.6 and 3.2 μM, respectively [1].

IC50 & Target

CDK2

3.6 μM (Km)

CDK5

3.2 μM (Km)

Molecular Weight

301.75

Formula

C₁₀H₁₂ClN₅O₂S

CAS No.

21886-12-4

SMILES

O=S(C1=CC=C(NC2=NC=NC(N)=C2)C=C1)(N)=O.[H]Cl

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

PNU112455ACDKCyclin dependent kinaseATPsiteanticooperativecompetitiveAlzheimer'sdiseaseInhibitorinhibitorinhibit

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产品名称:
PNU112455A hydrochloride
目录号:
HY-112468
需求量: