1. Immunology/Inflammation
  2. Toll-like Receptor (TLR)
  3. AXC-715 hydrochloride

AXC-715 hydrochloride  (Synonyms: T785 hydrochloride)

目录号: HY-138139A
产品使用指南

AXC-715 (T785) hydrochloride 是一种 TLR7/TLR8 双激动剂,从专利 WO2020168017 A1 中获得。AXC-715 可用于合成抗体佐剂免疫偶联物,偶联物包括一个与程序性死亡配体 1 (PD-L1) 连接到一个或多个佐剂的抗体结构上。

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AXC-715 hydrochloride Chemical Structure

AXC-715 hydrochloride Chemical Structure

CAS No. : 2490497-93-1

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生物活性

AXC-715 (T785) hydrochloride is a TLR7/TLR8 dual agonist, extracted from patent WO2020168017 A1[1]. AXC-715, compound D from WO2020190734A1, can be used for synthesis of antibody-adjuvant immunoconjugates, comprising an antibody construct that binds programmed death-ligand 1 (PD-L1) linked to one or more adjuvants[2].

IC50 & Target[1]

TLR8

 

TLR7

 

分子量

347.89

Formula

C18H26ClN5

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

AXC-715 hydrochloride 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
AXC-715 hydrochloride
目录号:
HY-138139A
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