1. PI3K/Akt/mTOR
    MAPK/ERK Pathway
    Apoptosis
  2. Akt
    mTOR
    p38 MAPK
    Apoptosis
  3. Rotundic acid

Rotundic acid 

目录号: HY-N2217
产品使用指南

Rotundic acid 是一种从圆形肠球菌 (I. rotunda) 中获得的三萜类化合物,可通过 AKT/mTORMAPK 途径在肝细胞癌中诱导 DNA 损伤和细胞凋亡。Rotundic acid 具有抗炎和保护心脏的能力。

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Rotundic acid Chemical Structure

Rotundic acid Chemical Structure

CAS No. : 20137-37-5

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Description

Rotundic acid, a triterpenoid obtained from I. rotunda, induces DNA damage and cell apoptosis in hepatocellular carcinoma through AKT/mTOR and MAPK Pathways. Rotundic acid possesses anti-inflammatory and cardio-protective abilities[1].

IC50 & Target

Akt

 

mTOR

 

p38 MAPK

 

Molecular Weight

488.70

Formula

C₃₀H₄₈O₅

CAS No.

20137-37-5

SMILES

C[C@@]1(CO)[C@@H](O)CC[C@]2(C)[C@@]3([H])CC=C4[C@]5([H])[C@](C)(O)[C@H](C)CC[C@@](C(O)=O)5CC[C@](C)4[C@@](C)3CC[C@@]12[H]

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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产品名称:
Rotundic acid
目录号:
HY-N2217
需求量: