1. GPCR/G Protein Metabolic Enzyme/Protease
  2. Oxytocin Receptor Endogenous Metabolite
  3. Oxytocin

Oxytocin  (Synonyms: 催产素; 缩宫素; α-Hypophamine; Oxytocic hormone)

目录号: HY-17571 纯度: 95.19%
COA 产品使用指南

Oxytocin (α-Hypophamine; Oxytocic hormone) 是一种多效的下丘脑肽 (hypothalamic peptide),有助于分娩、哺乳和亲社会行为。Oxytocin 可以作为一种压力应对分子,具有抗炎、抗氧化剂和保护作用,特别是在面对逆境或创伤时。

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Custom Peptide Synthesis

Oxytocin Chemical Structure

Oxytocin Chemical Structure

CAS No. : 50-56-6

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规格 价格 是否有货 数量
10 mM * 1 mL in DMSO ¥3600
In-stock
2 mg ¥650
In-stock
5 mg   询价  
10 mg   询价  

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Other Forms of Oxytocin:

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Top Publications Citing Use of Products
  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Oxytocin (α-Hypophamine; Oxytocic hormone) is a pleiotropic, hypothalamic peptide known for facilitating parturition, lactation, and prosocial behaviors. Oxytocin can function as a stress-coping molecule with anti-inflammatory, antioxidant, and protective effects especially in the face of adversity or trauma[1][2].

IC50 & Target

Human Endogenous Metabolite

 

体内研究
(In Vivo)

During the LMA task, rat core body temperature are modestly decreased. Oxytocin (subcutaneous injection; 0.1 mg/kg-0.3 mg/kg; single dose) produces significantly greater hypothermia (at 0.3 mg/kg) than either saline or the two lower doses of oxytocin. Oxytocin at 0.3 mg/kg produces a significantly greater decrease in temperature than vehicle between 15-60 min post injection, whereas 0.1 mg/kg slightly decreases temperature at the 30 min time point only[1].
Oxytocin (0.1 mg/kg) engages in significantly more body sniffing and ano-genital sniffing compared with saline controls. It also increases the total time spent in social interaction (71.6±4.3 s), compared to those receiving vehicle (56.9±4.1 s)[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Fifty-six male Lister-hooded rats (150-200 g)[1]
Dosage: 0.1 mg/kg-0.3 mg/kg
Administration: Subcutaneous injection; 0.1 mg/kg-0.3 mg/kg; single dose
Result: Produced significantly greater hypothermia (at 0.3 mg/kg) than the saline group.
分子量

1007.19

Formula

C43H66N12O12S2

CAS 号
性状

固体

颜色

White to off-white

Sequence

Cys-Tyr-Ile-Gln-Asn-Cys-Pro-Leu-Gly-NH2 (Disulfide bridge:Cys1-Cys6)

Sequence Shortening

CYIQNCPLG-NH2 (Disulfide bridge:Cys1-Cys6)

中文名称

催产素;缩宫素

结构分类
初始来源

the paraventricular and supraoptic nuclei of the hypothalamus

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

溶解性数据
In Vitro: 

DMSO 中的溶解度 : 100 mg/mL (99.29 mM; 超声助溶; 吸湿的 DMSO 对产品的溶解度有显著影响,请使用新开封的 DMSO)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 0.9929 mL 4.9643 mL 9.9286 mL
5 mM 0.1986 mL 0.9929 mL 1.9857 mL
查看完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效
储备液的保存方式和期限:-80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)。-80°C储存时,请在6个月内使用,-20°C储存时,请在1个月内使用。

  • 摩尔计算器

  • 稀释计算器

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量
=
浓度
×
体积
×
分子量 *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start)

C1

×
体积 (start)

V1

=
浓度 (final)

C2

×
体积 (final)

V2

动物溶解方案计算器
请输入动物实验的基本信息:

给药剂量

mg/kg

动物的平均体重

g

每只动物的给药体积

μL

动物数量

由于实验过程有损耗,建议您多配一只动物的量
计算结果
工作液所需浓度 : mg/mL
纯度 & 产品资料

纯度: 99.79%

参考文献

完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效
储备液的保存方式和期限:-80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)。-80°C储存时,请在6个月内使用,-20°C储存时,请在1个月内使用。

可选溶剂 浓度 溶剂体积 质量 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 0.9929 mL 4.9643 mL 9.9286 mL 24.8215 mL
5 mM 0.1986 mL 0.9929 mL 1.9857 mL 4.9643 mL
10 mM 0.0993 mL 0.4964 mL 0.9929 mL 2.4822 mL
15 mM 0.0662 mL 0.3310 mL 0.6619 mL 1.6548 mL
20 mM 0.0496 mL 0.2482 mL 0.4964 mL 1.2411 mL
25 mM 0.0397 mL 0.1986 mL 0.3971 mL 0.9929 mL
30 mM 0.0331 mL 0.1655 mL 0.3310 mL 0.8274 mL
40 mM 0.0248 mL 0.1241 mL 0.2482 mL 0.6205 mL
50 mM 0.0199 mL 0.0993 mL 0.1986 mL 0.4964 mL
60 mM 0.0165 mL 0.0827 mL 0.1655 mL 0.4137 mL
80 mM 0.0124 mL 0.0621 mL 0.1241 mL 0.3103 mL
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Oxytocin
目录号:
HY-17571
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