2. PI3K/Akt/mTOR Anti-infection
  3. Akt Bacterial
  4. 10-DEBC hydrochloride

10-DEBC hydrochloride 是选择性的 Akt 抑制剂，其 IC50 值为 1.28 μM。10-DEBC hydrochloride 也是抗肺结核的化合物。

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10-DEBC hydrochloride Chemical Structure

10-DEBC hydrochloride Chemical Structure

CAS No. : 925681-41-0

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Other Forms of 10-DEBC hydrochloride:

10-DEBC hydrochloride 相关抗体

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查看 Akt 亚型特异性产品:

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Akt Akt1 Akt2 Akt3

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

10-DEBC hydrochloride is a selective Akt inhibitor, with an IC50 of 1.28 μM. 10-DEBC hydrochloride is a novel anti-TB compound[1][2].

体外研究
(In Vitro)

10-DEBC is found to inhibit the growth of Mtb in whole-cell assay with an IC50 of 12.8 μM, while inhibiting replication of Mtb inside iMACs with an IC50 of 1.5 μM, without host cell toxicity even at the highest concentration of 25 μM[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

10-DEBC hydrochloride 相关抗体:
分子量

381.34

Formula

C20H26Cl2N2O
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

10-DEBC hydrochloride 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

10-DEBC925681-41-0AktBacterialPKBProtein kinase BtuberculosisreactiveoxygenspeciesROSInhibitorinhibitorinhibit

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产品名称：
10-DEBC hydrochloride
目录号：
HY-100654
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