ACLY - ATP citrate lyase Gene

中文名称：ATP 柠檬酸裂合酶

种属: Homo sapiens

同用名: ACL; ATPCL; CLATP

基因 ID: 47 | 基因类型: protein coding

关于 ACLY

Cytogenetic location: 17q21.2 Genomic coordinates (GRCh38): 17:41,866,917-41,930,545 (from NCBI)

This gene has 10 transcripts (splice variants) and 282 orthologues. Ubiquitous expression in prostate (RPKM 37.3), kidney (RPKM 29.2) and 25 other tissues.

功能概要

ATP 柠檬酸裂解酶是负责在许多组织中合成胞质乙酰辅酶 A 的主要酶。该酶是表面上相同的亚基的四聚体 (相对分子量约为 440,000) 。它催化柠檬酸和 CoA 形成乙酰辅酶 A 和草酰乙酸，同时 ATP 水解为 ADP 和磷酸盐。该产品乙酰辅酶 A 用于几种重要的生物合成途径，包括脂肪生成和胆固醇生成。在神经组织中，ATP 柠檬酸裂解酶可能参与乙酰胆碱的生物合成。已经为该基因鉴定了编码不同亚型的多个转录物变体。[RefSeq 提供，2014 年 12 月]

ATP Citrate Lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440,000) of apparently identical subunits. It catalyzes the formation of acetyl-CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. The product, acetyl-CoA, serves several important biosynthetic pathways, including lipogenesis and cholesterogenesis. In nervous tissue, ATP citrate-lyase may be involved in the biosynthesis of acetylcholine. Multiple transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Dec 2014]

ACLY 基因产物(5)

mRNA	Protein	Name
NM_198830.2	NP_942127.1	ATP-citrate synthase isoform 2
NM_001303275.1	NP_001290204.1	ATP-citrate synthase isoform 4
XM_005257395.2	XP_005257452.1	ATP-citrate synthase isoform X1
NM_001303274.1	NP_001290203.1	ATP-citrate synthase isoform 3
NM_001096.3	NP_001087.2	ATP-citrate synthase isoform 1

基因本体论

分子功能
生物过程
细胞组分

分子功能 GO 注释	逻辑证据	参考文献	来源
enables ATP citrate synthase activity	IDA IDA: 通过直接分析推断	1371749	GOA
enables protein binding	IPI IPI: 通过物理相互作用推断	23932781	GOA

生物过程 GO 注释	逻辑证据	参考文献	来源
involved in acetyl-CoA biosynthetic process	IDA IDA: 通过直接分析推断	1371749	GOA
involved in citrate metabolic process	IDA IDA: 通过直接分析推断	1371749	GOA
involved in fatty acid biosynthetic process	IDA IDA: 通过直接分析推断	10653665	GOA
involved in lipid biosynthetic process	IDA IDA: 通过直接分析推断	23932781	GOA
involved in oxaloacetate metabolic process	IDA IDA: 通过直接分析推断	1371749	GOA

细胞组分 GO 注释	逻辑证据	参考文献	来源
located in cytosol	IDA IDA: 通过直接分析推断	9116495	GOA

EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

ACLY 蛋白结构

ATP-grasp_2

CoA_binding

Ligase_CoA

Citrate_synt

0
200
400
600
800
1000
1101 a.a.

蛋白主名

其他名称

ATP-citrate synthase

ATP-citrate (pro-S-)-lyase

citrate cleavage enzyme

重组 ACLY 蛋白

目录号	产品名	蛋白编号	纯度
HY-P72070	ACLY Protein, Human (His-SUMO)	P53396 (K4-K265)	≥95%

ACLY 抗体

目录号	产品名	应用	反应物种
HY-P80380	ATP Citrate Lyase Antibody (YA596)	WB, ICC/IF, IHC-P, IP, FC	Human, Mouse
HY-P80560	ATP Citrate Lyase Antibody (YA829)	WB, ICC/IF, FC	Human, Mouse, Monkey
HY-P84388	ATP Citrate Lyase Antibody (YA4085)	WB, IHC-P, ICC/IF, FC, ELISA	Human, Mouse, Rat, Monkey, Rabbit

关联疾病

疾病名称

别名

Diabetes Mellitus

Diabetes

Soft Palate Cancer

Malignant Tumor Of Soft Palate	Malignant Tumor Of The Soft Palate
Palate Cancer Soft Palate

疾病名称	别名
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

相关产品

Approval

生物活性分子 (9)

目录号	产品名	作用方式	纯度	是否罕见病
HY-13001	Quizartinib		99.08%	是
HY-109539	Gemtuzumab ozogamicin	Inducer	98.00%	否
HY-B0091	Adapalene		99.98%	是
HY-14217	Quizartinib dihydrochloride		99.81%	否
HY-B0393	Fudosteine		98.0%	否
HY-B0491A	Carbazochrome sodium sulfonate		98.0%	否
HY-14277A	Levocabastine hydrochloride	Antagonist	99.3%	否
HY-B0091R	Adapalene (Standard)		/	否
HY-B0091A	Adapalene sodium salt		/	否

抗体抑制剂 (1)

目录号	产品名	作用方式	纯度	是否罕见病
HY-P9959	Inotuzumab ozogamicin		/	否

Clinical Phase

生物活性分子 (10)

目录号	产品名	作用方式	纯度	Phase
HY-156655A	Olgotrelvir sodium	Inhibitor	95.0%	Phase 3
HY-156655	Olgotrelvir	Inhibitor	/	Phase 3
HY-15527	Emapunil	Inhibitor	99.94%	Phase 2
HY-13535	ATN-161	Antagonist	99.36%	Phase 2
HY-106025	Radequinil	Antagonist	99.25%	Phase 2
HY-P1454	Fz7-21	Antagonist	99.59%	Phase 1
HY-12010	BMS-599626 Hydrochloride	Inhibitor	99.68%	Phase 1
HY-144289	BMS-820132	Activator	99.75%	Phase 1
HY-10251	BMS-599626	Inhibitor	98.56%	Phase 1
HY-132824	Ledaborbactam etzadroxil	Inhibitor	/	Phase 1

抗体抑制剂 (2)

目录号	产品名	作用方式	纯度	Phase
HY-P99362	Ensituximab	Inhibitor	99.93%	Phase 2
HY-P9992	Pelgifatamab	Inhibitor	99.884%	Phase 1

Pre-clinical Phase

生物活性分子 (499)

Cat. No.	产品名	作用方式	纯度	是否罕见病
HY-18657	TEPP-46	Activator	99.93%	否
HY-16990	Ac-YVAD-cmk	Inhibitor	98.94%	否
HY-44134	Dimethyl 2-oxoglutarate	Inhibitor	97.50%	否
HY-118297	Ac4ManNAz (80% α isomer)		99.74%	否
HY-100396	SQ22536	Inhibitor	99.98%	否
HY-16450	SB 204990	Inhibitor	99.75%	否
HY-W728531	Ac4ManNAz	Inhibitor	99.52%	否
HY-P1001	Ac-DEVD-CHO	Inhibitor	99.76%	否
HY-110288	3FAx-Neu5Ac		99.88%	否
HY-P1098	Ac2-26	Inhibitor	99.01%	否
HY-133870	Itaconate-alkyne		98.01%	否
HY-104032	Ac-CoA Synthase Inhibitor1	Inhibitor	99.70%	否
HY-124500	AC-4-130		99.93%	否
HY-141128	Ac4GalNAz		99.99%	否
HY-101801	Ac-Gly-BoroPro		98.0%	否
HY-Y1977	100mM Pro-Ac, 20 mM Arg, pH 5.0 buffer		99.29%	否
HY-127111	NDI-091143	Inhibitor	99.72%	否
HY-122214	AC-73	Inducer	99.84%	否
HY-15967	PS48	Activator	99.71%	否
HY-125798	2,3-Dehydro-2-deoxy-N-acetylneuraminic acid	Inhibitor	≥99.0%	否
HY-112942A	CMP-Sialic acid sodium salt		90.83%	否
HY-P1003	Ac-DEVD-AMC		99.93%	否
HY-P1098A	Ac2-26 TFA	Inhibitor	99.67%	否
HY-107636	DC_AC50	Inducer	99.98%	否
HY-111675	Ac-FLTD-CMK	Inhibitor	99.18%	否
HY-149302	MC4033		98.26%	否
HY-P1005	Ac-DEVD-AFC		99.59%	否
HY-124004	Acetyl-6-formylpterin		95.0%	否
HY-100958	4-DAMP		99.96%	否
HY-101279	ST034307	Inhibitor	99.11%	否
HY-145765	JQAD1		98.24%	否
HY-138159	Boc-Lys(Ac)-AMC		99.53%	否
HY-120019	Ac-YVAD-CHO	Inhibitor	98.23%	否
HY-W039953	Ac4GlcNAz		99.60%	否
HY-N2609	7,4'-Dihydroxyflavone	Inhibitor	99.64%	否
HY-122051	AC1903	Inhibitor	99.80%	否
HY-P1393	AC 187		98.86%	否
HY-160109	Ac5GalNTGc		98.39%	否
HY-P10149	Ac-IEPD-CHO	Inhibitor	99.61%	否
HY-P3236	N-Acetyl-Ile-Glu-Pro-Asp-p-nitroanilide	Substrate	99.77%	否
HY-103430A	SKF-83566	Antagonist	99.86%	否
HY-141866	Acid Ceramidase-IN-1	Inhibitor	99.36%	否
HY-123051	Ac-WLA-AMC		99.79%	否
HY-145237	BM213		99.81%	否
HY-P0034A	Ac-DEVD-CMK TFA	Inhibitor	99.07%	否
HY-P1093	Ac-LEHD-AFC		98.22%	否
HY-W014130	N-Acetyl-L-arginine		99.97%	否
HY-123052	Ac-PAL-AMC		≥98.0%	否
HY-147368	PKM2 activator 2	Activator	99.38%	否
HY-154818	Bovine Serum Albumin, Acetylated		/	否
HY-P1006	Ac-DEVD-pNA	Substrate	98.96%	否
HY-P1393A	AC 187 TFA		99.40%	否
HY-136744	Caspase-9 Inhibitor III	Inhibitor	99.00%	否
HY-79490	Ac-Exatecan	Inhibitor	99.02%	否
HY-123630	Allura Red AC		98.01%	否
HY-14350	AC-55541	Agonist	99.40%	否
HY-P1092	Ac-IEPD-AFC		99.97%	否
HY-P1169	Ac-IETD-AFC		99.28%	否
HY-P2377	Ac-YVAD-AFC		99.56%	否
HY-W004066	Ac-Ala-OH		≥98.0%	否
HY-100738	Ubiquitin Isopeptidase Inhibitor I, G5	Inducer	98.0%	否
HY-D1705	Ac-ANW-AMC		99.40%	否
HY-147286	Ac-Lys-Val-Cit-PABC-MMAE		99.94%	否
HY-148859	AA-T3A-C12		99.76%	否
HY-151852	9AzNue5Ac		≥95.0%	否
HY-32264	X-Neu5Ac sodium	Inhibitor	99.98%	否
HY-153750	Wnt pathway inhibitor 3	Inhibitor	98.96%	否
HY-P2091	Ac-YVAD-pNA		99.93%	否
HY-103195	NKY80	Inhibitor	99.76%	否
HY-163828	PPA24		98.09%	否
HY-P2617A	Ac-WEHD-AFC TFA		98.84%	否
HY-P5247	Palmitoyl tetrapeptide-20	Activator	99.67%	否
HY-W008986	Fmoc-Lys(Ac)-OH		99.79%	否
HY-P4417A	Ac-IEPD-AMC TFA		98.01%	否
HY-W102456	H-Phe(4-Ac)-OH		99.19%	否
HY-W1126504	ETN029	Ligand	99.91%	否
HY-P1368A	Stressin I TFA	Agonist	98.63%	否
HY-132197	CBP/p300-IN-12	Inhibitor	99.72%	否
HY-111554	AcLys-PABC-VC-Aur0101	Inhibitor	99.42%	否
HY-122025	AC-262536	Agonist	99.94%	否
HY-160821A	N-Acetylmannosamine 6-phosphate sodium salt		95.0%	否
HY-P1454A	Fz7-21 TFA	Antagonist	98.12%	否
HY-P3434A	Ac-FEID-CMK TFA	Inhibitor	97.06%	否
HY-N9459	2-Amino-2-deoxyglucose hydrochloride		98.0%	否
HY-108532	AC-261066	Agonist	99.27%	否
HY-116874	SKF 83822	Agonist	98.01%	否
HY-14351	AC-264613	Agonist	98.3%	否
HY-146356	Adenylyl cyclase type 2 agonist-1	Agonist	99.30%	否
HY-158123	PSMA binder-1		98.33%	否
HY-66007	Ac-β-Ala-OH		98.0%	否
HY-N2098	Obtusifolin	Inhibitor	99.91%	否
HY-P10201A	Ac-GpYLPQTV-NH2 acetate	Inhibitor	99.38%	否
HY-P1368	Stressin I	Agonist	98.20%	否
HY-116530	9-Cyclopentyladenine monomethanesulfonate	Inhibitor	99.95%	否
HY-124680	AC-263093 free base	Inhibitor	99.81%	否
HY-136727	Ac-LEVD-CHO	Inhibitor	98.41%	否
HY-147117	NHS-SS-Ac		95.0%	否
HY-161024	AC1Q3QWB	Inhibitor	99.39%	否
HY-P0232	Fmoc-Thr[GalNAc(Ac)3-α-D]-OH		99.08%	否
HY-P10235	Cyclic AC253	Antagonist	99.83%	否
HY-P2462	Ac-Arg-Gly-Lys(Ac)-AMC		99.86%	否
HY-W011982	Ac-DL-Trp-OH		99.49%	否
HY-21648	2'-OMe-Ac-C Phosphoramidite		99.53%	否
HY-P10639	C5aR2 agonist P32	Agonist	99.82%	否
HY-120833	Ac-Ile-Glu-Thr-Asp-pNA		99.90%	否
HY-108526	AC-55649	Agonist	99.70%	否
HY-148324	PKM2 activator 5	Activator	96.24%	否
HY-P1098B	Ac2-26 ammonium	Degrader	97.45%	否
HY-P3662	Ac-[Nle4,D-Phe7]-α-MSH (4-10)-NH2	Activator	99.50%	否
HY-P4449A	Ac-VRPR-AMC TFA		99.35%	否
HY-100336	AC260584	Agonist	99.48%	否
HY-108312A	Ac-VEID-CHO TFA	Inhibitor	99.77%	否
HY-138586	DMT-dC(ac) Phosphoramidite	Activator	99.76%	否
HY-14425	Peturadol	Inhibitor	98.7%	否
HY-144549	LXR agonist 1	Agonist	99.95%	否
HY-148041	ATPase-IN-2	Inhibitor	98.0%	否
HY-174216	PZL-A	Activator	99.72%	否
HY-D1652	Ac-LEHD-AMC	Chemical	98.96%	否
HY-P2016	Ac-Nle-Pro-Nle-Asp-AMC		99.85%	否
HY-P3455	Ac-SVVVRT-NH2	Modulator	98.68%	否
HY-P4764	Ac-(d-Arg)-CEH-(d-Phe)-RWC-NH2	Agonist	99.09%	否
HY-W016749	N-Acetyl-DL-aspartic acid		99.93%	否
HY-W145561	Neu5Acα(2-3)Galβ MP glycoside		99.43%	否
HY-150248	RNA splicing modulator 3	Modulator	98.58%	否
HY-151819	N3Ac-OPhOMe		98.21%	否
HY-45491	Dmt-2'-f-dc(ac) amidite		99.53%	否
HY-W077279	5'-O-DMT-N4-Ac-dC		97.16%	否
HY-W101367	Ac-Cys(Bzl)-OH		99.72%	否
HY-132934	Ac32Az19	Inhibitor	98.12%	否
HY-115748	Mant-GTPγS	Inhibitor	93.0%	否
HY-117851	AC-265347	Agonist	99.97%	否
HY-125604	WCK-4234	Inhibitor	98.0%	否
HY-13856	(R)-PS210	Inhibitor	98.09%	否
HY-145830	AC1-IN-1	Inhibitor	99.32%	否
HY-148043	Schnurri-3 inhibitor-1	Inhibitor	99.07%	否
HY-151516	microRNA-21-IN-2	Inhibitor	≥98.0%	否
HY-158118	Lys(CO-C3-p-I-Ph)-OMe		97.19%	否
HY-P10939A	Ac-DMLD-CMK TFA	Inhibitor	98.44%	否
HY-P1118	Ac9-25		98.14%	否
HY-P1448	Ac-Leu-Arg-AMC		98.17%	否
HY-P4846	Ac-Pro-Gly-Pro-OH	Agonist	99.49%	否
HY-P5983	Ac-VEID-AFC		99.26%	否
HY-W096146	Propynyl-PEG1-Ac		95.0%	否
HY-158783	SACLAC		99.70%	否
HY-18700	BRD73954	Inhibitor	98.0%	否
HY-153094	BDM-2	Inhibitor	99.09%	否
HY-103688	N-Ac-γ-Calicheamicin-AcBut-NHS ester		95.62%	否
HY-110157	AC-186	Agonist	99.61%	否
HY-124609	CAD031		99.39%	否
HY-141464	Fmoc-L-Asn(beta-D-GlcNAc(Ac)3)-OH		95.03%	否
HY-144287	Glucokinase activator 3		98.36%	否
HY-150246	RNA splicing modulator 1	Modulator	/	否
HY-170534	Ac-EEVC-OH		99.11%	否
HY-175606	EVT0185	Inhibitor	98.97%	否
HY-P0266B	N-Acetyl-Ser-Asp-Lys-Pro acetate		99.88%	否
HY-P0280	MUC5AC motif peptide		98.97%	否
HY-P10142	Ac-YEVD-AMC		99.59%	否
HY-P3115	Ac-LEVD-AFC		98.11%	否
HY-P3155	Ac-hMCH(6-16)-NH2	Agonist	99.94%	否
HY-P4547	Ac-Trp-Glu-His-Asp-AMC		99.84%	否
HY-P6079A	Ac-IHIHIYI-NH2 TFA		99.02%	否
HY-W012713	Ac-D-Ala-OH		98.0%	否
HY-13493	AC710	Inhibitor	99.13%	否
HY-164054	MicroRNA modulator-2	Modulator	99.54%	否
HY-W101366	AC-PHE-OME		99.87%	否
HY-P6825	PNT2001	Ligand	98.72%	否
HY-103430	SKF-83566 hydrobromide	Antagonist	/	否
HY-112942	CMP-Sialic acid		/	否
HY-115748A	Mant-GTPγS triammonium	Inhibitor	/	否
HY-118343	AC-93253	Inhibitor	99.3%	否
HY-125501	Biotin-XX hydrazide		95.43%	否
HY-134567A	Ac-VDVAD-CHO TFA	Inhibitor	99.15%	否
HY-137683A	Guanosine 5'-O-(2-thiodiphosphate) trisodium	Inhibitor	97.1%	否
HY-137918	TGF-βRI inhibitor 3	Inhibitor	99.16%	否
HY-138602	5'-O-DMT-N4-Ac-2'-F-dC		99.11%	否
HY-138612	5'-O-DMT-3'-O-TBDMS-Ac-rC		99.18%	否
HY-138614	5'-O-DMT-2'-O-TBDMS-Ac-rC		99.80%	否
HY-147286A	Ac-Lys-Val-Cit-PABC-MMAE formic		99.96%	否
HY-153613	Ac-PLVE-FMK	Inhibitor	98.0%	否
HY-154592	DMTr-TNA-G(O6-CONPh2)(N2Ac)-amidite		98.20%	否
HY-158125	PSMA binder-2		97.35%	否
HY-160109A	Ac5GalNTGc epimer	Inhibitor	98.39%	否
HY-173374	DOTAGA-FAP-2286-ALB	Inhibitor	/	否
HY-18234C	Leupeptin Ac-LL hydrochloride	Inhibitor	95.0%	否
HY-D1258	AC-green		98.04%	否
HY-D2869	Ac-H-FluNox		/	否
HY-E70445	Chondroitinase AC II		/	否
HY-N10772	Albanin A	Inhibitor	97.67%	否
HY-P10145	Ac-LEVD-pNA		99.17%	否
HY-P10781	PSMA-D5	Modulator	98.61%	否
HY-P10816	PACE4 Inhibitory peptide C23		/	否
HY-P2065	Ac-VEID-AMC		/	否
HY-P2717	Ac-YVAD-AMC	Inhibitor	99.64%	否
HY-P3318	Boc-Phe-Leu-Phe-Leu-Phe	Antagonist	98.03%	否
HY-P3761	Ac-Tyr-Val-Lys-Asp-aldehyde	Inhibitor	99.89%	否
HY-P4417	Ac-IEPD-AMC		/	否
HY-P4449	Ac-VRPR-AMC		/	否
HY-P5247A	Palmitoyl tetrapeptide-20 TFA	Activator	/	否
HY-P5378A	Ac-KQKLR-AMC TFA		/	否
HY-RS00166	ACLY Human Pre-designed siRNA Set A	Pre-designed Set	/	否
HY-W024554	AC-Asp(OtBU)-OH		99.48%	否
HY-W114327	N4-Acetyl-2'-O-methylcytidine		98.0%	否
HY-W145646	Fmoc-L-Ser((Ac)4-β-D-Glc)-OH		≥98.0%	否
HY-W214058	Ac-2-Nal-OH		/	否
HY-W415798	Ac4GalNAlk		/	否
HY-W570884	5-Me-dC(Ac) amidite		97.0%	否
HY-118806A	AC-42 hydrochloride	Agonist	98.42%	否
HY-154829A	AC-099 hydrochloride	Agonist	99.92%	否
HY-156287	GCase modulator-1	Modulator	97.0%	否
HY-16020	AC-430 hydrobromide	Inhibitor	99.70%	否
HY-163820	WIZ degrader 4	Degrader	99.37%	否
HY-164248	Ac-rG		99.69%	否
HY-171910	tri(GalNAc-PEG2)-PEG4-cyclo(Ac-DCAW-{Arg(3F-Ph)-PEG2}-LGELVWCT) (Cys2-Cys12)	Ligand	99.46%	否
HY-P10336	Serpinin	Agonist	98.74%	否
HY-W114328	DMT-OMe-rC(Ac)		≥97.0%	否
HY-W131753	2'-F-Ac-C		99.64%	否
HY-13001S	Quizartinib-d8		/	否
HY-163608	Ac-macropa		/	否
HY-B0091S	Adapalene-d3		/	否
HY-101863	CB-6673567	Inhibitor	/	否
HY-103411	SKF83822 hydrobromide	Agonist	/	否
HY-106530	Gitoformate		/	否
HY-106560	Proglumetacin	Inhibitor	/	否
HY-108487	N-Acetyl-O-phosphono-Tyr-Glu dipentylamide	Inhibitor	/	否
HY-113844A	Ac-Gly-Lys-OMe acetate		/	否
HY-113963	Ac-IETD-CHO	Inhibitor	98.59%	否
HY-115443	MZH29	Inhibitor	/	否
HY-117118A	AC-90179	Agonist	/	否
HY-117616	Laurotetanine	Inhibitor	/	否
HY-117867A	AVE-8063 hydrochloride		/	否
HY-118464	AC915		/	否
HY-118806	AC-42	Agonist	/	否
HY-120019A	Ac-YVAD-CHO acetate	Inhibitor	/	否
HY-121738	TC AC 28	Inhibitor	/	否
HY-125673	AC-178335		/	否
HY-126232	Verproside		/	否
HY-128433	CK1-IN-3	Inhibitor	99.00%	否
HY-130629	VHC-7	Agonist	/	否
HY-131805A	3'-O-Ac-dGTP sodium		/	否
HY-134567	Ac-VDVAD-CHO	Inhibitor	/	否
HY-134684	Mal-PEG3-O-Ac		/	否
HY-135020	AC-24,055		/	否
HY-135070	Ac-RLR-AMC		/	否
HY-135070B	Ac-RLR-AMC TFA		/	否
HY-135244	Imazamethabenz-methyl		/	否
HY-135392S	N-Desmethyl Pimavanserin-d9 hydrochloride		/	否
HY-136727A	Ac-LEVD-CHO TFA	Inhibitor	/	否
HY-136728	Ac-YVAD-AOM	Inhibitor	/	否
HY-136733	Ac-DNLD-CHO	Inhibitor	/	否
HY-138583	Ac-dA Phosphoramidite		/	否
HY-140343	Ac4GalNAl		/	否
HY-141077	N-(Ac-PEG3)-N'-(azide-PEG3)-Cy7 chloride		/	否
HY-141127	Azido-PEG4-tetra-Ac-beta-D-glucose		/	否
HY-14277	Levocabastine	Antagonist	/	否
HY-143463	AC-386	Inhibitor	/	否
HY-147397	PKM2 activator 3	Activator	/	否
HY-148313	PKM2 activator 4	Activator	/	否
HY-148415	Ac-Phe-Gly-pNA		/	否
HY-149552	Ac4-5SGlcNAc		/	否
HY-150658S	DMT-2′O-TBDMS-rA(ac)-1-15N phosphoramidite		/	否
HY-153614	Ac-VLPE-FMK	Inhibitor	99.0%	否
HY-154213	5’-O-DMTr-5-MedC (Ac)-methyl phosphonamidite		/	否
HY-155229	CBP/p300-IN-21	Inhibitor	/	否
HY-156020	Glucocerebrosidase-IN-2	Inhibitor	/	否
HY-158119A	PSMA-trillium		/	否
HY-158776	SLU-10482	Inhibitor	/	否
HY-159095	PKR activator 5	Activator	/	否
HY-159593	Ac-NH-(S,R,S)-AHPC-CO-cyclohexane-pyrimidine-diazabicyclo		/	否
HY-159601	CSN5-IN-1	Inhibitor	/	否
HY-161160	Ac4ManNDAz		/	否
HY-161519	PKM2 activator 7	Activator	/	否
HY-162665	WIZ degrader 1	Inducer	/	否
HY-162689	GprA	Agonist	/	否
HY-162837	AURKA against 1	Inhibitor	/	否
HY-163818	WIZ degrader 2	Degrader	/	否
HY-163819	WIZ degrader 3	Degrader	/	否
HY-163951	(S,R,S)-AHPC-Ac		/	否
HY-163952	(S,R,S)-AHPC-Ac-CO-cyclohexene-Bpin		/	否
HY-168656	Ac-Atovaquone	Inhibitor	/	否
HY-169263	AC10142A	Inhibitor	/	否
HY-169824	TRPML modulator 1	Inducer	/	否
HY-170841	HDAC3/BRD4-IN-1	Inhibitor	/	否
HY-171279	Casein kinase 1δ-IN-29		/	否
HY-171489	Mal-VC-PAB-EDA-N-Ac-Calicheamicin		/	否
HY-171960	SHP2-IN-40	Inhibitor	/	否
HY-172914	ACLY-IN-1	Inhibitor	/	否
HY-173135	PROTAC KDM4 degrader-1		/	否
HY-174151	XSJ110		/	否
HY-175589	XSJ81		/	否
HY-175744	PSMA-MAL-5	Ligand	/	否
HY-175755	Ac-BIM-acid bromide	Inhibitor	/	否
HY-176060	Platelet aggregation-IN-3	Ligand	/	否
HY-176063	TRPV1 antagonist 11		/	否
HY-176804	(R,S,R)-AHPC-Me-Ac		/	否
HY-177062	NPRA agonist-11	Agonist	/	否
HY-177136	ACLY-IN-2	Inhibitor	/	否
HY-178336	AC-340		/	否
HY-178360	NP1192		/	否
HY-178485	SJY26	Inhibitor	/	否
HY-179014	OGG1 activator-1	Activator	/	否
HY-179204	7-MAD-MDCPT-AC-(s-cyclopropane)		/	否
HY-18234B	Leupeptin Ac-LL	Inhibitor	/	否
HY-402873	DMTr-2'-O-C16-rC(Ac)-3'-CE-phosphoramidite	Inhibitor	/	否
HY-48668	AcLys-PABC-VC-Aur0101 intermediate-1		/	否
HY-79490S	Ac-Exatecan-d5	Inhibitor	99.93%	否
HY-CE01449	Ac-Lys(CoA)-NH2		/	否
HY-D2379A	closed-HMRG		/	否
HY-E70019	alpha-2-3,6-sialidase (BiNanH2)		/	否
HY-E70621	Sialic acid aldolase (Pm NaNa)		/	否
HY-N10628	Neu5Acα(2-6) N-Glycan		/	否
HY-N15826	RBM1-151	Substrate	/	否
HY-N8356	13-cis-Vitamin A palmitate		/	否
HY-N8356A	9-cis-Vitamin A palmitate		/	否
HY-P0034	Ac-DEVD-CMK	Inhibitor	/	否
HY-P0211	[Ac-Tyr1,D-Phe2]GRF 1-29, amide (human)	Antagonist	/	否
HY-P1001A	Ac-DEVD-CHO TFA		/	否
HY-P10070	Ac-pSar16-OH		/	否
HY-P10082	Ac-VETD-AMC		/	否
HY-P10083	Ac-VQVD-pNA		/	否
HY-P10084	Ac-VAD-pNA		/	否
HY-P10144	Ac-Orn-Phe-Arg-AMC		/	否
HY-P10146	Ac-LETD-CHO	Inhibitor	/	否
HY-P10147	Ac-LDESD-AMC	Inhibitor	/	否
HY-P10161	Ac-DMQD-pNA		/	否
HY-P10162	Ac-DMQD-AMC		/	否
HY-P10162A	Ac-DMQD-AMC TFA		/	否
HY-P10175	Acetalin-1	Antagonist	/	否
HY-P10176	Acetalin-2		/	否
HY-P10177	Acetalin-3	Antagonist	/	否
HY-P10201	Ac-GpYLPQTV-NH2	Inhibitor	/	否
HY-P10215	Ac-{Cpg}-Thr-Ala-{Ala(CO)}-Asp-{Cpg}-NH2	Inhibitor	/	否
HY-P10231	Ac-Phe-Thiaphe-OH		/	否
HY-P10236	Ac-WEHD-pNA		/	否
HY-P10240	Ac-WVAD-AMC		/	否
HY-P10241	Ac-LEHD-CHO	Inhibitor	/	否
HY-P10243	Ac-VAD-CMK	Inhibitor	/	否
HY-P10244	Ac-YVAD-FMK	Inhibitor	/	否
HY-P10276	Ac-VAD-AFC		/	否
HY-P10452	Ac-LEVDGWK(Dnp)-NH2		/	否
HY-P10656	Ac-DEVDD-TPP	Inducer	/	否
HY-P10667	Ac-MRGDH-NH2		/	否
HY-P10706	Ac-ILVAGK-NH2		/	否
HY-P10939	Ac-DMLD-CMK	Inhibitor	/	否
HY-P10955	Ac-AAVALLPAVLLALLAPVAD-CHO TFA	Inhibitor	/	否
HY-P11154	HAV peptide	Modulator	/	否
HY-P1118A	Ac9-25 TFA		/	否
HY-P11198	AC-P19M		/	否
HY-P11212	Ac-RHKK(Ac)-AMC		/	否
HY-P11213	Ac-RYQK(Ac)-AMC		/	否
HY-P11297	AC-SDKP-NH2		/	否
HY-P11325	Ac-RR-AFC TFA	Substrate	/	否
HY-P11326	Ac-FR-AFC TFA	Substrate	/	否
HY-P1169A	Ac-IETD-AFC TFA		/	否
HY-P1200	Ac-Tyr(PO3H2)-Glu-Glu-Ile-Glu-OH	Inhibitor	/	否
HY-P1200A	Ac-Tyr(PO3H2)-Glu-Glu-Ile-Glu-OH TFA	Inhibitor	/	否
HY-P1316	Ac-RYYRWK-NH2	Antagonist	/	否
HY-P1316A	Ac-RYYRWK-NH2 TFA	Agonist	/	否
HY-P1318	Ac-RYYRIK-NH2	Agonist	/	否
HY-P1318A	Ac-RYYRIK-NH2 TFA	Agonist	/	否
HY-P2285	AC 253	Antagonist	/	否
HY-P2374	Ac-DMQD-CHO	Inhibitor	/	否
HY-P2413	Ac-PPPHPHARIK-NH2	Inhibitor	/	否
HY-P2610	Ac-VEID-pNA	Activator	/	否
HY-P2615	Ac-VDVAD-AFC		/	否
HY-P2615A	Ac-VDVAD-AFC TFA		/	否
HY-P2620	Ac-LETD-AFC		/	否
HY-P2633A	Dentonin TFA		/	否
HY-P2939	Chondroitinase AC		/	否
HY-P2977	N-Acetylneuraminate lyase (CgNal)		/	否
HY-P3110	Ac-DNLD-AMC		/	否
HY-P3307	Ac-Val-Gln-aIle-Val-aTyr-Lys-NH2		/	否
HY-P3362	Ac-IETD-AMC		/	否
HY-P3364	Ac-QPKK(Ac)-AMC		/	否
HY-P3434	Ac-FEID-CMK	Inhibitor	/	否
HY-P3690	Ac-Leu-Leu-Norleucinol	Inhibitor	/	否
HY-P3729	Ac-Lys-D-Ala-D-Ala-OH		/	否
HY-P3940	Ac-MBP (4-14) Peptide		/	否
HY-P4019	Ac-Ser-Gln-Asn-Tyr-Pro-Val-Val-NH2		/	否
HY-P4039	Ac-EEVVAC-pNA		/	否
HY-P4040	Ac-D-DGla-LI-Cha-C	Inhibitor	/	否
HY-P4408	Ac-Arg-Gly-Lys-AMC		/	否
HY-P4416	Ac-Gly-Ala-Lys(Ac)-AMC		/	否
HY-P4443	Ac-GAK-AMC		/	否
HY-P4448	Ac-Gly-Pro-AFC		/	否
HY-P4519	Ac-Lys(Ac)-D-Ala-D-Lactic acid	Substrate	/	否
HY-P4521	Ac-Pro-Leu-Gly-[(S)-2-mercapto-4-methyl-pentanoyl]-Leu-Gly-OEt		/	否
HY-P4532	Ac-Leu-Val-Lys-Aldehyde	Inhibitor	/	否
HY-P4535	Ac-Trp-Glu-His-Asp-Aldehyde	Inhibitor	/	否
HY-P4665	Ac-c[Cys-Glu-His-d-Phe-Arg-Trp-d-Cys]-Pro-Pro-Lys-Asp-NH2	Antagonist	/	否
HY-P4688	(Ser(Ac)4,D-Ser(tBu)6,Azagly10)-LHRH		/	否
HY-P4787	Ac-Glu-Asp(EDANS)-Lys-Pro-Ile-Leu-Phe-Phe-Arg-Leu-Gly-Lys(DABCYL)-Glu-NH2		/	否
HY-P4832	Acetyl-Tau Peptide (273-284) amide	Inhibitor	/	否
HY-P5045	Fmoc-Thr(GalNAc(Ac)3-β-D)-OH		/	否
HY-P5280	Ac-KQL-AMC		/	否
HY-P5378	Ac-KQKLR-AMC		/	否
HY-P5525	AC3-I, myristoylated	Inhibitor	/	否
HY-P5830A	Biotin-DEVD-CHO TFA	Inhibitor	/	否
HY-P5922	PTD2	Inhibitor	/	否
HY-P5936	Ac-AAVALLPAVLLALLAP-DEVD-CHO	Inhibitor	/	否
HY-P5938	Ac-AAVALLPAVLLALLAP-YVAD-CHO	Inhibitor	/	否
HY-P5955	Ac-AAVALLPAVLLALLAP-LEVD-CHO	Inhibitor	/	否
HY-P5956	Ac-AAVALLPAVLLALLAP-LEHD-CHO	Inhibitor	/	否
HY-P6079	Ac-IHIHIYI-NH2		/	否
HY-R01635	hsa-miR-548ac mimic		/	否
HY-R01635A	hsa-miR-548ac agomir		/	否
HY-RI01635	hsa-miR-548ac inhibitor		/	否
HY-RI01635A	hsa-miR-548ac antagomir		/	否
HY-RS00167	Acly Mouse Pre-designed siRNA Set A	Pre-designed Set	/	否
HY-RS00168	Acly Rat Pre-designed siRNA Set A	Pre-designed Set	/	否
HY-RS05088	FRA10AC1 Human Pre-designed siRNA Set A	Pre-designed Set	/	否
HY-RS05955	H2AC18 Human Pre-designed siRNA Set A	Pre-designed Set	/	否
HY-RS08844	MUC5AC Human Pre-designed siRNA Set A	Pre-designed Set	/	否
HY-W004066S	Ac-Ala-OH-d3		99.0%	否
HY-W004066S1	Ac-Ala-OH-d4		/	否
HY-W010389S2	Ac-DL-Ala-OH-d4		/	否
HY-W011254	Ac-VAD-CHO	Inhibitor	/	否
HY-W012713S	Ac-D-Ala-OH-d4		99.0%	否
HY-W013322	Ac-Tyr-OEt.H2O		98.0%	否
HY-W014130A	N-Acetyl-L-arginine dihydrate		/	否
HY-W015241	Ac-D-Glu-OH		/	否
HY-W015241S	Ac-D-Glu-OH-d5		99.0%	否
HY-W016584	4,5-Dichlorocatechol	Inhibitor	/	否
HY-W040802	AC-94149		90.0%	否
HY-W042357S	Ac-rC Phosphoramidite-15N		/	否
HY-W042357S1	Ac-rC Phosphoramidite-15N2		/	否
HY-W042357S2	Ac-rC Phosphoramidite-15N3		/	否
HY-W042357S3	Ac-rC Phosphoramidite-13C2,d1		/	否
HY-W042357S4	Ac-rC Phosphoramidite-13C9		/	否
HY-W042357S5	Ac-rC Phosphoramidite-13C,d1		/	否
HY-W042357S6	Ac-rC Phosphoramidite-13C9,15N3		/	否
HY-W044285	Fmoc-D-4-Aph(cBm)-OH		/	否
HY-W048674	Fmoc-Ser(Ac)-OH		97.40%	否
HY-W101384	Ac-D-2-Nal-OH		99.93%	否
HY-W145531	Neu5GcAc[1Me,478Ac,9N3]-β-SPh		/	否
HY-W145540	Galβ(1-3)[Neu5Acα(2-6)]GalNAc-α-pNP		/	否
HY-W145548	GlcNPhth[36Bn,4Ac]-β-MP		/	否
HY-W145609	Neu5Troc[1Me,4789Ac]α(2-3)Gal[26Bn]-β-MP		/	否
HY-W145622	Galβ(1-3)[Neu5Acα(2-6)]GlcNAc-β-pNP		/	否
HY-W393498	Phenyl 2,4,6-tri-O-acetyl-3-O-allyl-β-D-thiogalactopyranoside		/	否
HY-W560922	Piperazine-Ac-OMe		/	否
HY-W560961	3',5'-TIPS-N-Ac-Adenosine		/	否
HY-W713878	Ac-VDVAD-pNA		/	否
HY-W766388	2-Amino-2-deoxyglucose hydrochloride-13C6		/	否
HY-W768178	2-Amino-2-deoxyglucose hydrochloride-13C2		/	否
HY-W854187	2'-Ome-Ac-G Phosporamidite		/	否
HY-Y1977A	100mM Pro-Ac, pH 5.0 buffer		99.29%	否
HY-10658	AC-7954		/	否
HY-108312	Ac-VEID-CHO	Inhibitor	/	否
HY-110209	AC4	Antagonist	/	否
HY-113844	Ac-Gly-Lys-OMe		/	否
HY-120278	4-Ethoxyquinazoline		/	否
HY-121248	Hydramethylnon	Inhibitor	/	否
HY-129027	Ac-Leu-Gly-Lys(Ac)MCA		/	否
HY-129648	AC-7954 free base		/	否
HY-131804A	3'-O-Acetyl-2'-deoxycytidine-5'-O-triphosphate tetrasodium		/	否
HY-131806A	3'-O-Ac-dTTP sodium		/	否
HY-134373A	Bis-Cl-ANT-ATP tetrasodium	Inhibitor	/	否
HY-13493A	AC710 Mesylate	Inhibitor	/	否
HY-138165	Ac-Phe-NH2		/	否
HY-154036	5′-DMTr-dC (Ac)-Methylphosphonamidite		/	否
HY-154829	AC-099	Agonist	/	否
HY-157171	Ac-YR-NH2	Modulator	/	否
HY-157232	AC Antibody purification resin 2		/	否
HY-157233	AC Antibody purification resin 1		/	否
HY-157235	AC Antibody affinity resin		/	否
HY-158792	GK241		/	否
HY-161021	AC2 selective-IN-1		/	否
HY-161913	AC-4-248	Inhibitor	/	否
HY-162159	Ac-Cys-NHMe		/	否
HY-163106	W000113414_I13	Agonist	/	否
HY-164053	MicroRNA modulator-1	Modulator	99.58%	否
HY-164249	DMT-rG(Ac)		/	否
HY-164253	TBS-rG(Ac)		/	否
HY-171289	Neu5Acα2-6GalNAcα1-4GlcNac		/	否
HY-171463	AC-271337		/	否
HY-177531	S-Ac7-DOg		/	否
HY-177738	6'Nicotinate Ac4ManNAz		/	否
HY-19647	Ritipenem acoxil	Inhibitor	/	否
HY-20560	(Ac)Phe-Lys(Alloc)-PABC-PNP		/	否
HY-43565C	(1S,9R)-Ac-Exatecan		/	否
HY-N12336	Gnetuhainin I		/	否
HY-N12894	(Z,E)-7,11-Hexadecadienyl acetate		/	否
HY-N12920	(Z)-3-Dodecenyl acetate		/	否
HY-P10639A	C5aR2 agonist P32 acetate	Agonist	/	否
HY-P10657	Ac-DEMEEC-OH	Inhibitor	/	否
HY-P10666	Ac-VDQQD-pNA		/	否
HY-P10668	Ac-EVKKQR-pNA	Inhibitor	/	否
HY-P3234	Ac-ESMD-CHO	Inhibitor	/	否
HY-RS17212	Muc5ac Mouse Pre-designed siRNA Set A	Pre-designed Set	/	否
HY-RS23664	Muc5ac Rat Pre-designed siRNA Set A	Pre-designed Set	/	否
HY-W042357	Ac-rC Phosphoramidite		98.87%	否
HY-W129441	N-Acetyl-4-S-cysteaminylphenol		/	否
HY-W130878	4-Octylphenol	Activator	/	否
HY-W338079	Ac-Asp-Glu-Val-Asp-pNA	Substrate	/	否
HY-W415799	(2S)-Ac4GalNAl		/	否
HY-W780787	(E,Z)-3,13-Octadecadienyl acetate		/	否
HY-W783407	Ac-rG Phosporamidite		/	否
HY-W881463	N4-Ac-C-(S)-GNA phosphoramidite		/	否
HY-P1734	Ac-MBP (1-11)		/	否

抗体抑制剂 (3)

Cat. No.	产品名	作用方式	纯度	是否罕见病
HY-P990012	Vamikibart	Inhibitor	≥99.0%	否
HY-P99715	Losatuxizumab	Inhibitor	99.44%	否
HY-P991512	SGN-30	Inducer	/	否

直系同源

种属	基因名	来源	基因 ID
Felis catus	ACLY	VGNC	VGNC:59513
Canis familiaris	ACLY	VGNC	VGNC:37511
Macaca mulatta	ACLY	VGNC	VGNC:99112
Rattus norvegicus	ACLY	RGD	RGD:2018
Bos taurus	ACLY	VGNC	VGNC:25543
Mus musculus	ACLY	MGD	MGI:103251
Others	ACLY	NCBI

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