1. Immunology/Inflammation
    Cytoskeleton
    Metabolic Enzyme/Protease
  2. Toll-like Receptor (TLR)
    MyD88
    Dynamin
    Mitochondrial Metabolism
  3. Schaftoside

Schaftoside 

目录号: HY-N0703
产品使用指南

Schaftoside 是在多种中草药(如 Eleusine indica)中发现的黄酮类化合物。Schaftoside 抑制 TLR4 和 Myd88 表达。 Schaftoside 还降低 Drp1 表达和磷酸化,并减少线粒体分裂。

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Schaftoside Chemical Structure

Schaftoside Chemical Structure

CAS No. : 51938-32-0

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Description

Schaftoside is a flavonoid found in a variety of Chinese herbal medicines, such as Eleusine indica. Schaftoside inhibits the expression of TLR4 and Myd88. Schaftoside also decreases Drp1 expression and phosphorylation, and reduces mitochondrial fission[1].

In Vitro

Schaftoside inhibits three pro-inflammatory enzymatic activities: secretory phospholipase A2 (sPLA2), lipoxygenase (LOX), and cyclooxygenase 2 (COX-2). Schaftoside also inhibits mRNA and protein expressions of proinflammatory cytokines(IL-1β, TNF-α, and IL-6)[1].

Molecular Weight

564.49

Formula

C₂₆H₂₈O₁₄

CAS No.

51938-32-0

SMILES

OC1=C([C@@H]([C@@H]([C@@H](O)[C@@H]2O)O)O[C@@H]2CO)C(O)=C3C(OC(C4=CC=C(O)C=C4)=CC3=O)=C1[C@H](OC[C@H](O)[C@@H]5O)[C@@H]5O

Shipping

Room temperature in continental US; may vary elsewhere

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
  • 摩尔计算器

  • 稀释计算器

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This equation is commonly abbreviated as: C1V1 = C2V2

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× = ×
C1   V1   C2   V2

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产品名称:
Schaftoside
目录号:
HY-N0703
需求量:

Schaftoside

Cat. No.: HY-N0703