2. GPCR/G Protein Neuronal Signaling Immunology/Inflammation
  3. Histamine Receptor
  4. Triprolidine

Triprolidine 是一种具有口服活性组胺H1受体拮抗剂 (H1R Antagonist)。Triprolidine 具有阻滞脊髓运动和知觉功能。Triprolidine 可用于过敏性鼻炎的研究。

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Triprolidine Chemical Structure

Triprolidine Chemical Structure

CAS No. : 486-12-4

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Triprolidine 的其他形式现货产品:

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Triprolidine 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Triprolidine is an orally active H1R Antagonist antagonist. Triprolidine has the function of spinal cord motor and sensory block. Triprolidine can be used for the research of allergic rhinitis[1][2][3].

体外研究
(In Vitro)

Triprolidine (maturing human dendritic cells) can antagonist histamine H1 and decreases the expression of CD45[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Triprolidine 相关抗体:
体内研究
(In Vivo)

Triprolidine (292.81-1467.20 μg/kg; i.p.; Male Sprague-Dawley rat) produces a dose-dependent effect of spinal motor and sensory block in rats[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Male Sprague-Dawley rat (300-350 g)[2]
Dosage: 292.81, 488.02, 733.60, 1098.83 and 1467.20 μg/kg
Administration: Intrathecal injection
Result: Elicited spinal block in a dose-dependent.
分子量

278.39

Formula

C19H22N2
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Triprolidine 相关分类

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  • 稀释计算器

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Triprolidine486-12-4Histamine Receptorantihistamineallergic rhinitisspinalmotorsensoryInhibitorinhibitorinhibit

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目录号：
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