1. Immunology/Inflammation
  2. Toll-like Receptor (TLR)
  3. MD2-TLR4-IN-1

MD2-TLR4-IN-1 

目录号: HY-128598
产品使用指南

MD2-TLR4-IN-1 (compound 22m) 是 MD2-TLR4 复合体的抑制剂,能够抑制巨噬细胞 LPS 诱导的 TNF-α 和 IL-6 的表达,IC50 值分别为 0.89 μM 和 0.53 μM。

MCE 的所有产品仅用作科学研究,我们不为任何个人用途提供产品和服务

MD2-TLR4-IN-1 Chemical Structure

MD2-TLR4-IN-1 Chemical Structure

CAS No. : 2249801-12-3

1.  客户无需承担相应的运输费用。

2.  同一机构(单位)同一产品试用装仅限申领一次,同一机构(单位)一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户

Size Stock
100 mg Get quote
250 mg Get quote
500 mg Get quote

* Please select Quantity before adding items.

Customer Review

Top Publications Citing Use of Products
  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

Description

MD2-TLR4-IN-1 (compound 22m) is an inhibitor of myeloid differentiation protein 2/toll-like receptor 4 (MD2-TLR4) complex, inhibiting lipopolysaccharides (LPS)-induced expression of tumor necrosis factor alpha (TNF-α) and interleukin-6 (IL-6) in macrophages with IC50 values of 0.89 μM and 0.53 μM, respectively[1].

IC50 & Target

MD2-TLR4[1].

Molecular Weight

421.28

Formula

C₂₂H₁₄Cl₂N₄O

CAS No.

2249801-12-3

SMILES

ClC1=C(C(NC2=CC(C(C3=CC=C(NC=C4)C4=C3)=NN5)=C5C=C2)=O)C(Cl)=CC=C1

Shipping

Room temperature in continental US; may vary elsewhere

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

您最近查看的产品:

Your information is safe with us. * Required Fields.

   产品名称:

 

* 需求量:

* 客户姓名:

 

* Email:

* 电话:

 

* 公司或机构名称:

   留言给我们:

Bulk Inquiry

Inquiry Information

产品名称:
MD2-TLR4-IN-1
目录号:
HY-128598
需求量:

MD2-TLR4-IN-1

Cat. No.: HY-128598