1. Flavonoids
  2. 6-Hydroxyflavone

6-Hydroxyflavone 

目录号: HY-N7110 纯度: 99.88%
产品使用指南

6-Hydroxyflavone 是一种天然存在的黄酮化合物,具有抗炎作用。6-Hydroxyflavone 对牛血红蛋白 (BHb) 糖基化具有抑制作用。6-Hydroxyflavone 能激活 AKT、ERK 1/2、JNK 信号通路,有效促进成骨细胞分化。6-Hydroxyflavone 能抑制 LPS 诱导的 NO 的产生。

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6-Hydroxyflavone Chemical Structure

6-Hydroxyflavone Chemical Structure

CAS No. : 6665-83-4

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Description

6-Hydroxyflavone is a naturally occurring flavone, with anti-inflammatory activity. 6-Hydroxyflavone exhibits inhibitory effect towards bovine hemoglobin (BHb) glycation. 6-Hydroxyflavone can activate AKT, ERK 1/2, and JNK signaling pathways to effectively promote osteoblastic differentiation. 6-Hydroxyflavone inhibits the LPS-induced NO production[1] [2].

Molecular Weight

238.24

Formula

C₁₅H₁₀O₃

CAS No.

6665-83-4

SMILES

O=C1C=C(C2=CC=CC=C2)OC3=CC=C(O)C=C13

Shipping

Room temperature in continental US; may vary elsewhere

Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 125 mg/mL (524.68 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.1974 mL 20.9872 mL 41.9745 mL
5 mM 0.8395 mL 4.1974 mL 8.3949 mL
10 mM 0.4197 mL 2.0987 mL 4.1974 mL
* 请根据产品在不同溶剂中的溶解度,选择合适的溶剂配制储备液,并请注意储备液的保存方式和期限。
In Vivo:

请根据您的实验动物和给药方式选择适当的溶解方案,配制前请先配制澄清的储备液,再依次添加助溶剂 (为保证实验结果的可靠性,体内实验的工作
液,建议您现用现配,当天使用;澄清的储备液可以根据储存条件,适当保存;以下溶剂前的百分比是指该溶剂在您配制终溶液中的体积占比):

  • 1.

    请依序添加每种溶剂: 10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.08 mg/mL (8.73 mM); Clear solution

  • 2.

    请依序添加每种溶剂: 10% DMSO    90% corn oil

    Solubility: ≥ 2.08 mg/mL (8.73 mM); Clear solution

*以上所有助溶剂都可在 MCE 网站选购。
References
  • 摩尔计算器

  • 稀释计算器

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This equation is commonly abbreviated as: C1V1 = C2V2

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× = ×
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产品名称:
6-Hydroxyflavone
目录号:
HY-N7110
需求量:

6-Hydroxyflavone

Cat. No.: HY-N7110