2. Gene
  3. MICAL1 - microtubule associated monooxygenase, calponin and LIM domain containing 1 Gene

MICAL1 - microtubule associated monooxygenase, calponin and LIM domain containing 1 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：含微管相关的单加氧酶、钙调蛋白和 LIM 结构域 1

种属: Homo sapiens

同用名: MICAL; NICAL; MICAL-1

基因 ID: 64780 | 基因类型: protein coding

关于 MICAL1

Cytogenetic location: 6q21 Genomic coordinates (GRCh38): 6:109,444,062-109,465,968 (from NCBI)

This gene has 8 transcripts (splice variants), 198 orthologues, 36 paralogues and is associated with 1 phenotype. Ubiquitous expression in bone marrow (RPKM 31.4), lymph node (RPKM 25.8) and 23 other tissues.

功能概要

该基因编码一种酶，可氧化肌动蛋白上的甲硫氨酸残基，从而促进肌动蛋白丝的解聚。这种蛋白质与 NEDD9/CAS-L (表达的神经前体细胞，发育下调 9) 相互作用并调节信号传导。可变剪接导致多个转录本变体。[RefSeq 提供，2015 年 8 月]

This gene encodes an enzyme that oxidizes methionine residues on actin, thereby promoting depolymerization of actin filaments. This protein interacts with and regulates signalling by NEDD9/CAS-L (neural precursor cell expressed, developmentally down-regulated 9). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2015]

MICAL1 基因产物(3)

mRNA Protein Name
NM_001159291.2 NP_001152763.1 [F-actin]-monooxygenase MICAL1 isoform 2
NM_001286613.2 NP_001273542.1 [F-actin]-monooxygenase MICAL1 isoform 3
NM_022765.4 NP_073602.3 [F-actin]-monooxygenase MICAL1 isoform 1

MICAL1 蛋白结构

FAD_binding_3

FAD_binding_3: FAD binding domain (85 - 122)

CH

CH: Calponin homology (CH) domain (512 - 610)

LIM

LIM: LIM domain (697 - 750)

DUF3585

DUF3585: Protein of unknown function (DUF3585) (926 - 1059)

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  • 1067 a.a.
蛋白主名 其他名称

[F-actin]-monooxygenase MICAL1

NEDD9-interacting protein with calponin homology and LIM domains

关联疾病

疾病名称 别名
Epilepsy, Familial Temporal Lobe, 1

ETL1

Adpeaf

Adlte

Epilepsy, Partial, With Auditory Features

Autosomal Dominant Partial Epilepsy With Auditory Features

Epilepsy, Lateral Temporal Lobe, Autosomal Dominant

Familial Temporal Lobe Epilepsy 1

Partial Epilepsy With Auditory Features

Autosomal Dominant Lateral Temporal Lobe Epilepsy

Lateral Temporal Lobe Epilepsy Autosomal Dominant

Epilepsy, Temporal Lobe, Familial, Type 1
Epilepsy, Familial Temporal Lobe, 7

Familial Temporal Lobe Epilepsy 7

ETL7

Epilepsy, Temporal Lobe, Familial, Type 7
Cerebral Amyloid Angiopathy, Itm2b-Related, 1

Dementia, Familial British

Fbd

Presenile Dementia With Spastic Ataxia

Familial British Dementia

Abri Amyloidosis

Cerebral Amyloid Angiopathy, British Type

Itm2b-Related Cerebral Amyloid Angiopathy 1

Familial Dementia, British Type

Cerebral Amyloid Angiopathy, Itm2b-Related 1

CAA-ITM2B1

Cerebral Amyloid Angiopathy British Type

Dementia, Familial, British
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

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Approval
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纯度 是否罕见病
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HY-109506 DPPC 99.91% 否
HY-109044 Tapinarof Agonist 99.95% 否
HY-B1192 Estradiol benzoate Agonist 99.90% 否
HY-B0448 Phenytoin Inhibitor 99.95% 是
HY-147080 Avacincaptad pegol sodium Inhibitor 98.53% 否
HY-124290 Carotegrast methyl Antagonist 99.24% 否
HY-B0892 Benzyl alcohol 99.99% 否
HY-B0448A Phenytoin sodium Inhibitor 99.78% 是
HY-B0111 Drospirenone Agonist 98.45% 否
HY-B0693 Ranitidine Antagonist ≥99.0% 是
HY-B1350A Fusidic acid sodium salt Inhibitor 99.64% 是
HY-B0281A Ranitidine hydrochloride Antagonist 99.86% 是
HY-B1198 Piperonyl butoxide Inhibitor ≥98.0% 否
HY-13859 Clevudine Inhibitor 99.93% 否
HY-B1640R Ethacrynic acid (Standard) Inhibitor 98.78% 否
HY-B1268 Docusate Sodium Inhibitor ≥98.0% 否
HY-12752A Alimemazine hemitartrate 98.44% 否
HY-P0009 Cetrorelix Antagonist / 否
HY-B0693A Ranitidine bismuth citrate / 否
HY-B1198R Piperonyl butoxide (Standard) Inhibitor / 否
HY-133171A (S)-Norfluoxetine Inhibitor / 否
HY-B0430B (±)-Pantothenic acid / 否
抗体抑制剂 (2)
目录号 产品名 作用方式
纯度 是否罕见病
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目录号 产品名 作用方式
纯度 Phase
HY-N0594 Deacetylasperulosidic Acid Inhibitor 99.86% Phase 4
HY-139994 XN methyl pyrazole Inducer / Phase 4
HY-163885 SSZ Inhibitor / Phase 4
HY-70062 Pevonedistat 99.98% Phase 3
HY-10484 Pevonedistat hydrochloride 99.19% Phase 3
HY-123475 Sisunatovir Inhibitor 99.40% Phase 3
HY-123475A Sisunatovir hydrochloride Inhibitor 98.61% Phase 3
HY-B1640A Ethacrynic acid sodium / Phase 3
HY-100442 Paquinimod Inhibitor 99.90% Phase 2
HY-141523 Vociprotafib Inhibitor 99.70% Phase 2
HY-10367 Canertinib Inhibitor 99.74% Phase 2
HY-14530 Pelitrexol 98.07% Phase 2
HY-129239 Farudodstat 99.68% Phase 2
HY-10367A Canertinib dihydrochloride Inhibitor 99.68% Phase 2
HY-18099 S1RA Antagonist 99.43% Phase 2
HY-137440 Firazorexton 99.94% Phase 2
HY-137440A Firazorexton hydrate 99.94% Phase 2
HY-106887 SCH 32615 99.68% Phase 2
HY-14866 Raseglurant Modulator 99.65% Phase 2
HY-168739 Topoisomerase I inhibitor 17 / Phase 2
HY-116175 BIBB 515 99.44% Phase 1
HY-125639 (rac)-AR-13503 Inhibitor 99.08% Phase 1
HY-115681 (2R/S)-6-PNG Inhibitor 99.88% Phase 1
HY-111792 GSK1795091 Agonist 94.48% Phase 1
HY-106925 Cetefloxacin Inhibitor / Phase 1
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抗体抑制剂 (2)
目录号 产品名 作用方式
纯度 Phase
HY-P9983 Lintuzumab Inhibitor 98.09% Phase 3
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Pre-clinical Phase
生物活性分子 (533)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-14452 Fatostatin Inhibitor 99.85% 否
HY-N0219 Bicuculline Antagonist 99.97% 否
HY-44134 Dimethyl 2-oxoglutarate Inhibitor 97.50% 否
HY-134901 WM-3835 99.78% 否
HY-110171 iMDK Inhibitor 99.35% 否
HY-160769 NIBR-LTSi Activator 99.97% 否
HY-131042 NNMTi Inhibitor 99.70% 否
HY-N2342 Procyanidin C1 Inducer 99.54% 否
HY-113354 Anserine 99.85% 否
HY-Y0505 Trichloroacetic acid 99.01% 否
HY-120912 Gingerenone A Activator 99.95% 否
HY-103124 DOI hydrochloride Agonist 99.61% 否
HY-14452A Fatostatin hydrobromide Inhibitor 99.52% 否
HY-126255 SBI-797812 Activator 99.88% 否
HY-103157 PD146176 99.59% 否
HY-B1005 8-Hydroxyquinoline Inhibitor 99.99% 否
HY-103017A JH-X-119-01 Inhibitor 99.03% 否
HY-P1925A GO-203 TFA 99.28% 否
HY-137207 MK-28 Activator 99.88% 否
HY-143228 SH-42 99.80% 否
HY-160818 MC3138 Activator 99.27% 否
HY-156856 FL118-14-Propanol 98.69% 否
HY-114169 WRG-28 Inhibitor 99.76% 否
HY-131181 LEI-401 Inhibitor 99.73% 否
HY-117427 D5D-IN-326 99.90% 否
HY-P1587 IRBP (1-20), human 99.62% 否
HY-135747 Gut restricted-7 Inhibitor 98.23% 否
HY-124284 Hexamethylene bisacetamide 99.56% 否
HY-P1290A PKA Inhibitor Fragment (6-22) amide TFA Inhibitor 99.87% 否
HY-134494 MS48107 99.90% 否
HY-108559 L-161982 Inhibitor 99.30% 否
HY-111754 DMX-5804 Inhibitor 99.83% 否
HY-W010042 L-Glucose 99.88% 否
HY-110171A iMDK quarterhydrate Inhibitor 99.37% 否
HY-P1136C TAT-Gap19 TFA 99.41% 否
HY-W013411A Locostatin 99.88% 否
HY-156117 LB244 Inhibitor 98.08% 否
HY-P1136B TAT-Gap19 99.10% 否
HY-N1388 Tussilagone 99.46% 否
HY-W016145 L-Glutamic acid monosodium (hydrate) Inducer ≥98.0% 否
HY-110197 6bK TFA 99.35% 否
HY-103111 MMPIP hydrochloride Antagonist 99.10% 否
HY-103017 JH-X-119-01 hydrochloride Inhibitor 99.14% 否
HY-110190 VU0422288 Modulator 99.94% 否
HY-113365 Cholestenone 99.81% 否
HY-147323 Ferulic acid 4-O-sulfate 98.07% 否
HY-145721A Mongersen sodium 99.61% 否
HY-161834 RG100204 Inhibitor 99.50% 否
HY-101404A L-Homocysteine thiolactone hydrochloride 99.99% 否
HY-103400 8-Chloroadenosine 99.97% 否
HY-113412A 3-Methylhistamine dihydrochloride 99.80% 否
HY-B1002 Oxolinic acid Inhibitor 98.97% 否
HY-B1946 Dimethoate 99.91% 否
HY-145628 CM398 99.85% 否
HY-119347 Cirsilineol Inhibitor ≥98.0% 否
HY-125130 Hesperetin 7-O-glucoside Inhibitor 98.66% 否
HY-127034 Antipain dihydrochloride Inhibitor 95.0% 否
HY-155157 PF-07247685 Inhibitor 98.66% 否
HY-19350 BML-210 98.04% 否
HY-N6869 Dehydroabietic acid 98.52% 否
HY-N6962 α-Spinasterol 99.15% 否
HY-161305 SE-7552 Inhibitor 99.48% 否
HY-101029 MBM-55 99.94% 否
HY-N0901A Corynoxine B Inhibitor 99.76% 否
HY-N2189 Swertisin 99.54% 否
HY-N7271 Solanidine 99.90% 否
HY-W345885 Saccharic acid Inhibitor ≥98.0% 否
HY-116818 Crebinostat Inhibitor 99.79% 否
HY-12242 GBR 12935 dihydrochloride Inhibitor 99.80% 否
HY-114918 MS438 Agonist 99.85% 否
HY-116392B DL-threo-PDMP hydrochloride Inhibitor 99.40% 否
HY-120597 SAK3 Activator 99.80% 否
HY-129297 CMPF 99.57% 否
HY-116538 (10E,12Z)-Octadeca-10,12-dienoic acid Activator 99.10% 否
HY-101325 BRL 37344 sodium Agonist 99.90% 否
HY-103290 R715 Antagonist 99.67% 否
HY-12678S1 Entrectinib-d8 99.82% 否
HY-145313 TTBK1-IN-2 Inhibitor 99.91% 否
HY-15805 KIN-8194 Inhibitor 98.01% 否
HY-N1109 Uvaol Inducer 99.20% 否
HY-N5106 (E)-Flavokawain A Inducer 99.79% 否
HY-N8522 9,10-Dihydroxystearic acid ≥98.0% 否
HY-P3102 GLP-1(32-36)amide 98.44% 否
HY-171034 PQA-18 Inhibitor 99.62% 否
HY-107527 Org 25543 hydrochloride Inhibitor 99.93% 否
HY-147222 SAE-14 Antagonist 98.60% 否
HY-155478 Androgen receptor-IN-6 Inhibitor 98.26% 否
HY-D0887 Disodium 5'-inosinate 99.74% 否
HY-101325A BRL-37344 Agonist / 否
HY-108497 L-803087 Agonist 99.66% 否
HY-121852 SCH 336 Agonist 98.63% 否
HY-126193 JS-K 99.59% 否
HY-136182A YM-244769 Inhibitor 99.22% 否
HY-145721 Mongersen Inhibitor / 否
HY-155156 PF-07238025 Inhibitor 99.46% 否
HY-B2046 Simazine 99.44% 否
HY-P1259A PR-39 TFA Inhibitor 99.89% 否
HY-W018171 3,5,6-Trichloro-2-pyridinol 99.85% 否
HY-148506 5'-ODMT cEt m5U Phosphoramidite (Amidite) 99.25% 否
HY-120000 MS402 Inhibitor 98.36% 否
HY-132302 Hu7691 Inhibitor 99.91% 否
HY-160023 Elisrasib Inhibitor 98.50% 否
HY-100384 NKL 22 Inhibitor 97.26% 否
HY-101139A Xanthine amine congener hydrochloride Antagonist 98.03% 否
HY-136182 YM-244769 dihydrochloride Inhibitor 98.57% 否
HY-143312E (S)-V-0219 hydrochloride Modulator 99.71% 否
HY-143793 RBP4 inhibitor 1 Inhibitor 99.74% 否
HY-163087 PT-91 Agonist 98.25% 否
HY-N0506 Rosarin 99.96% 否
HY-P10032A NN1177 TFA 98.66% 否
HY-P1302 Orphanin FQ(1-11) Agonist 99.52% 否
HY-W248594 IR 813 tosylate 99.47% 否
HY-164546 WB436B 99.93% 否
HY-N10991 Crocetin dialdehyde 99.21% 否
HY-145774 PD-1/PD-L1-IN-23 Inhibitor 99.98% 否
HY-120589 VU0360172 Agonist 98.07% 否
HY-121035 7BIO Inhibitor 99.20% 否
HY-139659 ARD-61 99.57% 否
HY-162683 (S)-PHA533533 Inhibitor 98.27% 否
HY-N3522 Platycoside E Inhibitor 99.40% 否
HY-P2203 SAHM1 Inhibitor 96.40% 否
HY-N2736 3′,4′,7-Trihydroxyflavone Inhibitor ≥98.0% 否
HY-120083 Rodatristat Inhibitor 98.41% 否
HY-100442S1 Paquinimod-d5-1 Inhibitor 98.19% 否
HY-139973 OAB-14 99.21% 否
HY-162866 CXM102 Activator 98.58% 否
HY-164397 XMU-MP-5 99.00% 否
HY-N1503 Methyl deacetylasperulosidate 98.49% 否
HY-N7026 Celosin I 99.36% 否
HY-P1949A Cyclic MKEY TFA 98.47% 否
HY-W677042 α-Androstenol Modulator 97.03% 否
HY-Y1809 1-Hydroxyoctadecane 98.89% 否
HY-113354S Anserine-d4 99.38% 否
HY-P5489 IGRP(206-214) Agonist 96.40% 否
HY-120872 AJS1669 free acid Activator 99.15% 否
HY-136522 S2116 98.05% 否
HY-B0448S Phenytoin-d10 Inhibitor ≥98.0% 否
HY-100935 Cimaterol Agonist 99.13% 否
HY-100967 SKF 91488 dihydrochloride Inhibitor 98.62% 否
HY-118282 mPGES1-IN-7 Inhibitor 99.78% 否
HY-124609 CAD031 99.39% 否
HY-129087 BC-​1258 Inducer 99.26% 否
HY-144899 ASR-490 Inhibitor 99.05% 否
HY-156374 D359-0396 Inhibitor 99.98% 否
HY-162387 UK4b Inhibitor 96.17% 否
HY-162428 PTPN2/1-IN-3 Inhibitor / 否
HY-163729 I-BET787 Inhibitor 99.88% 否
HY-N9173 Cupressuflavone 99.32% 否
HY-W013411 (E/Z)-Locostatin Control 99.52% 否
HY-164478 G-631 Inhibitor 99.88% 否
HY-174400 SGLT2-IN-2 Inhibitor / 否
HY-20874 Deschlorodemethyldiazepam 99.47% 否
HY-101030A MBM-17S / 否
HY-156856S FL118-14-Propanol-d5 / 否
HY-103327 MJ15 Antagonist 99.78% 否
HY-106947 SY-640 99.77% 否
HY-107659 YM-244769 hydrochloride Inhibitor 99.02% 否
HY-108623 Atizoram Inhibitor 96.3% 否
HY-112636 Astrophloxine Inhibitor 98.34% 否
HY-113878 12-OAHSA ≥99.0% 否
HY-120514 JNc-440 98.04% 否
HY-121271 Kadsurin 99.38% 否
HY-12678S Entrectinib-d4 Inhibitor / 否
HY-130136 TMPRSS6-IN-1 Inhibitor / 否
HY-130136A TMPRSS6-IN-1 TFA Inhibitor / 否
HY-151876 Glucocorticoid receptor modulator 1 99.79% 否
HY-156276 SP4e Activator 99.72% 否
HY-156277 SP4f Activator 99.77% 否
HY-156842 MCAAD-3 96.12% 否
HY-156936 RCB-02-4-8 99.3% 否
HY-160237 HYL001 Inhibitor 99.94% 否
HY-161853 TX-2552 Inhibitor 99.69% 否
HY-162596 NRL-1049 Inhibitor 99.87% 否
HY-162765 TRPV4-IN-5 Inhibitor 98.77% 否
HY-163782 SMIP-031 / 否
HY-164495 Sob-AM2 Agonist / 否
HY-167862A UCM-05194 ammonium Agonist / 否
HY-173591 T0080 / 否
HY-18164 TASP0277308 Antagonist 99.00% 否
HY-19015 Probimane Inhibitor 99.91% 否
HY-21193 Perfluoropentanoic acid 98.0% 否
HY-21196A Potassium perfluorohexanesulfonate 98.0% 否
HY-B1002R Oxolinic acid (Standard) Inhibitor 97.60% 否
HY-D1065 NIR-H2O2 / 否
HY-N3204 Neoechinulin A Inhibitor ≥98.0% 否
HY-N5097 13-Oxo-9E,11E-octadecadienoic acid Activator / 否
HY-N7514 Strictosidinic acid Inhibitor / 否
HY-N9794 Isoboldine ≥95.0% 否
HY-P10032 NN1177 99.77% 否
HY-P5117 TAT-CIRP Inhibitor 98.32% 否
HY-X0009A JSH-009 dimaleate Inhibitor / 否
HY-114853 BVT.13 Agonist / 否
HY-12242A GBR 12935 Inhibitor / 否
HY-160554 C12-113 / 否
HY-B1946S Dimethoate-d6 97.90% 否
HY-N16039 TAN-1030A Activator / 否
HY-101029A MBM-55S / 否
HY-101030 MBM-17 / 否
HY-120667 DS-5272 / 否
HY-12459 Pyrindamycin B Inhibitor / 否
HY-132302A Hu7691 free base Inhibitor / 否
HY-139798 Iboxamycin Inhibitor / 否
HY-153262 (7R)-Elisrasib Inhibitor 99.52% 否
HY-B1198S Piperonyl butoxide-d9 Inhibitor / 否
HY-100782 DL-AP7 Antagonist / 否
HY-10084 CK0106023 Inhibitor / 否
HY-100922 N-Acetylglycyl-D-glutamic acid Agonist / 否
HY-10109A AS-605240 potassium Inhibitor / 否
HY-101699 AMG-076 free base Antagonist / 否
HY-101726 DuP 105 Inhibitor 99.38% 否
HY-101780A Tinostamustine hydrochloride Inhibitor / 否
HY-103177 PSB-10 hydrochloride Inhibitor / 否
HY-103357 LY288513 Antagonist / 否
HY-103567 Desmethyl-YM-298198 hydrochloride Antagonist / 否
HY-105052 SC 34301 / 否
HY-105236 (Rac)-Enadoline Agonist / 否
HY-105969 Dichloromethotrexate / 否
HY-106752 CI-936 Agonist / 否
HY-106837 Israpafant Antagonist / 否
HY-107503 MMPIP Antagonist / 否
HY-107504 VU0360172 hydrochloride Agonist 98.94% 否
HY-107567 Carcinine Antagonist / 否
HY-108497A L-803087 TFA Agonist / 否
HY-108538 Ethacrynic acid D5 Inhibitor / 否
HY-110020 rel-O-2050 Antagonist / 否
HY-111315 XEN103 Inhibitor / 否
HY-113354S1 Anserine-d4 hydrochloride / 否
HY-113866 E-55888 Agonist / 否
HY-113889 ZK112993 Antagonist / 否
HY-114542 LY 201409 / 否
HY-114651 Phenazoviridin / 否
HY-116046 GR 196429 Agonist / 否
HY-116597 L-783483 Agonist / 否
HY-117081 C30(ω-hydroxy) Ceramide (d18:1/30:0) / 否
HY-117569 KF24345 free base Inhibitor / 否
HY-117603 CM-10-18 Inhibitor / 否
HY-117836 FAK-IN-16 Inhibitor / 否
HY-118030 RQ-00311651 Antagonist / 否
HY-118032 Bozepinib / 否
HY-118426 (Rac)-Tipifarnib Inhibitor / 否
HY-118574 UBP141 Antagonist / 否
HY-119519 OB-2 Inhibitor / 否
HY-119899 BO-0742 / 否
HY-120171 DH-376 Inhibitor / 否
HY-120225 NJK14047 Inhibitor / 否
HY-120561 PC-046 / 否
HY-120769 Pimprinine Inhibitor ≥90.0% 否
HY-120828 Albenatide Agonist / 否
HY-121431 FR-901235 / 否
HY-12153 JNJ-1930942 Modulator / 否
HY-121565 SaRI 59-801 Activator / 否
HY-122179 NUCC-555 Antagonist / 否
HY-122309 A-71497 / 否
HY-122518 8-Deazafolic acid Inhibitor / 否
HY-122655 HMCEF Inhibitor / 否
HY-122817 FR900098 sodium Inhibitor / 否
HY-122916 7-Acetyllycopsamine / 否
HY-123020 CYD-2-88 Antagonist / 否
HY-123237 KRC-108 / 否
HY-123357 IMM-H004 Inhibitor / 否
HY-123733A MIP-1095 TFA 99.76% 否
HY-124412S Paynantheine-d3 / 否
HY-124557 Mahanimbine Inhibitor / 否
HY-126152 Chlorthiamid ≥90.0% 否
HY-126185 Nibroxane Inhibitor / 否
HY-126835 A924 / 否
HY-126910 Mesyl Salvinorin B Agonist / 否
HY-127039 Antipain Inhibitor / 否
HY-129335 Chlorozotocin Inhibitor / 否
HY-129406 AF 698 / 否
HY-130581 Lipid X Inhibitor / 否
HY-131508 M&B 5124 Inhibitor / 否
HY-131954 5-HT3 antagonist 4 Antagonist / 否
HY-133533 O-2050 Antagonist / 否
HY-134191 Cryptochrome modulator 1 Modulator / 否
HY-138842 DDN Activator / 否
HY-143312C (S)-V-0219 Modulator / 否
HY-144668 RdRP-IN-4 Inhibitor / 否
HY-146001 Influenza virus-IN-4 Inhibitor / 否
HY-146151 γ-Secretase modulator 12 / 否
HY-146280 mGAT3/4-IN-1 Inhibitor / 否
HY-146293 HDAC6/HSP90-IN-1 Inhibitor / 否
HY-146297 Xanthine oxidoreductase-IN-2 Inhibitor / 否
HY-146401 CXCR4 antagonist 6 Antagonist / 否
HY-146435 Anti-inflammatory agent 22 Inhibitor / 否
HY-146458 Antibacterial agent 102 Inhibitor / 否
HY-146495 Antitubercular agent-19 Inhibitor / 否
HY-146496 Antitubercular agent-20 Inhibitor / 否
HY-146505 Tubulin polymerization-IN-6 / 否
HY-147335 6,9,12,15-Hexadecatetraenoic acid-ethyl ester / 否
HY-147529 mGluR2 modulator 3 Modulator / 否
HY-147678 GPR40 agonist 5 Agonist / 否
HY-147692 COX-2-IN-14 Inhibitor / 否
HY-148038 5-HT3 antagonist 5 Antagonist 99.75% 否
HY-148617 ALDH2 modulator 1 Modulator / 否
HY-149227 IDO1-IN-21 Inhibitor / 否
HY-149240 Anticancer agent 108 Inhibitor / 否
HY-149298 PSMA-IN-2 Inhibitor / 否
HY-149333 BO-1 Inhibitor / 否
HY-149521 PI3K-IN-47 Inhibitor / 否
HY-149776 RGH-560 / 否
HY-149940 SIMR3030 Inhibitor / 否
HY-149975 AMPA receptor modulator-4 Activator / 否
HY-150036 Anthramycin Antagonist / 否
HY-15041 NVP-SAA164 Antagonist / 否
HY-151153 HDAC1-IN-5 / 否
HY-153322 ITK degrader 2 Degrader / 否
HY-155229 CBP/p300-IN-21 Inhibitor / 否
HY-155236 Ancistrotecine B Inhibitor / 否
HY-155328 GK444 Inhibitor / 否
HY-155329 GK718 Inhibitor / 否
HY-155529 FD1024 Inhibitor / 否
HY-155548 RORγt inverse agonist 31 Inhibitor / 否
HY-155652 ABCG2-IN-1 Inhibitor / 否
HY-155682 Antibacterial agent 150 Inhibitor / 否
HY-156792 RIOK2-IN-1 Inhibitor / 否
HY-157014 TPT-004 Inhibitor 99.90% 否
HY-157085 BX-2819 Inhibitor / 否
HY-157211 Anti-inflammatory agent 66 Inhibitor / 否
HY-157326 hMAO-B-IN-6 Inhibitor / 否
HY-157429 25N-N1-Nap Agonist / 否
HY-157430 BET-IN-21 Inhibitor / 否
HY-158006 SDX-7539 Inhibitor / 否
HY-158272 Penicillin/OVA Inhibitor / 否
HY-158434 IRAK1-IN-1 Inhibitor / 否
HY-158649 Fasnall benzenesulfonate / 否
HY-159602 BET BD2-IN-3 Inhibitor / 否
HY-159891 Microtubule destabilizing agent-2 / 否
HY-159895 PAR4 antagonist 7 Antagonist / 否
HY-159941 tau-0N4R-IN-1 Inhibitor / 否
HY-159942 5-HT7R antagonist 3 / 否
HY-159972 PKR1 antagonist 1 Antagonist / 否
HY-160025 IDO antagonist-1 Antagonist / 否
HY-160550 DPM-1003 Inhibitor / 否
HY-161281 α-Glucosidase-IN-49 Inhibitor / 否
HY-161372 PARP1/c-Met-IN-1 / 否
HY-161373 PI3Kα-IN-22 Inhibitor / 否
HY-161458 GSK-3β inhibitor 16 / 否
HY-161671 GAT2711 Agonist 98.00% 否
HY-161781 HVH-2930 Inhibitor 96.54% 否
HY-161860 Antibacterial agent 233 Inhibitor / 否
HY-161863 Tubulin polymerization-IN-67 / 否
HY-161887 SMARCA2-IN-8 Inhibitor / 否
HY-161890 Antimycobacterial agent-8 Inhibitor / 否
HY-161893 Anti-MRSA agent 15 Inhibitor / 否
HY-161901 BC-1293 Inhibitor / 否
HY-162406 UNC8969 / 否
HY-162655A SLF80821178 hydrochloride Inhibitor / 否
HY-162703 Lipid-lowering agent-2 Activator / 否
HY-162727 GCS-12 / 否
HY-162751 Anticancer agent 249 / 否
HY-162760 COMT-IN-1 Inhibitor / 否
HY-162867 Photosensitizer-5 Inducer / 否
HY-162879 FAK inhibitor 7 / 否
HY-162893 SX29 Inhibitor / 否
HY-163003 Antitrypanosomal agent 19 Inhibitor / 否
HY-163066 α-Glucosidase-IN-44 Inhibitor / 否
HY-163300 NLRP3-IN-30 Inhibitor / 否
HY-163320 AChE/Aβ-IN-5 Inhibitor / 否
HY-163363 β-AR antagonist 2 Antagonist / 否
HY-163482 ELQ-596 Inhibitor / 否
HY-163484 ELQ-650 Inhibitor / 否
HY-163651 (R)-Vorbipiprant Antagonist / 否
HY-163797 WRN inhibitor 10 Inhibitor / 否
HY-163799 PRMT5-MTA-IN-1 Inhibitor / 否
HY-163816 Antiproliferative agent-53-d3 Inhibitor / 否
HY-163817 PARP1/2-IN-3 Inhibitor / 否
HY-163906 Anti-MRSA agent 16 Inhibitor / 否
HY-163978 YGZ-331 Activator / 否
HY-165425 KR31173 Antagonist / 否
HY-168021 MAO-A/SERT-IN-1 Inhibitor / 否
HY-168031 AChE/BChE-IN-21 / 否
HY-168444 CDK4/6-IN-23 Inhibitor / 否
HY-168742 V1a/V2 antagonist 1 Antagonist / 否
HY-169007 STAT3-IN-34 Inhibitor / 否
HY-169019 XJTU-L453 / 否
HY-169037 Δ8-Tetrahydrocannabinoquinone Inducer / 否
HY-169104 InhA-IN-8 Inhibitor / 否
HY-169240 MX69-102 Activator / 否
HY-169394 5-HT1AR agonist 2 / 否
HY-169928 WRN inhibitor 14 Inhibitor / 否
HY-170659 NF-κB-IN-18 Inhibitor / 否
HY-170900 SJ44236 Degrader / 否
HY-170934 BW710 Inhibitor / 否
HY-170977 JAK1/STAT3-IN-1 Inhibitor / 否
HY-171035 PRL-295 Inhibitor / 否
HY-171732 FANFT / 否
HY-172456 JSF-4898 Inhibitor / 否
HY-172674 HPK1-IN-59 Inhibitor / 否
HY-172732 PRMT5-IN-50 Inhibitor / 否
HY-172781 HDAC6-IN-55 Inhibitor / 否
HY-172930 PVTX-405 / 否
HY-173267 CES2A-IN-2 Inhibitor / 否
HY-173313 Ferroptosis-IN-19 Inhibitor / 否
HY-173316 STING-IN-12 Inhibitor / 否
HY-173347 BLINK11 Inhibitor / 否
HY-173348 BLINK15 Inhibitor / 否
HY-173471 TRPA1 agonist-1 Agonist / 否
HY-173479 GLP-1R agonist 30 Agonist / 否
HY-175042 D-myo-Inositol-1,3,4,5,6-pentaphosphate ammonium salt Inhibitor / 否
HY-176052 PPO-allene Inhibitor / 否
HY-176063 TRPV1 antagonist 11 / 否
HY-176127 JX10 Inhibitor / 否
HY-176288 eIF4E/eIF4G PPI-IN-1 / 否
HY-176775 TPP-IOA Inhibitor / 否
HY-40156A Mycobacterium Tuberculosis-IN-5 Inhibitor / 否
HY-B0693S Ranitidine-d6 / 否
HY-B1002S Oxolinic acid-d5 Inhibitor 98.0% 否
HY-B2046S Simazine-d10 / 否
HY-D1056A5 Lipopolysaccharides, from E. coli K-235 Activator / 否
HY-D1066 NIR-Thiol dinitrobenzenesulfonate / 否
HY-D1535 IR 813 perchlorate / 否
HY-D2095 Medical fluorophore 33 / 否
HY-D2203 BODIPY BDP4 / 否
HY-N0219R Bicuculline (Standard) Antagonist / 否
HY-N10312 Yadanzigan Inhibitor / 否
HY-N10341 Centaureidin Activator / 否
HY-N10359 Isoandrographolide Inhibitor / 否
HY-N11021 Feruloyl tyramine / 否
HY-N11723 Catenarin Inhibitor / 否
HY-N12042 Taxamairin B Inhibitor / 否
HY-N12124 Monascuspiloin 95% 否
HY-N12249 7-Deoxy-trans-dihydronarciclasine Inhibitor / 否
HY-N12353 Stevisalioside A Inhibitor / 否
HY-N15177 Δ9-THCB Agonist / 否
HY-N15703 Norisocorydine / 否
HY-N4243 Neocurdione / 否
HY-N5126 Juncusol / 否
HY-N7047 8-Epidiosbulbin E acetate Inhibitor 98.42% 否
HY-N7271R Solanidine (Standard) / 否
HY-N7944 Eucommiol / 否
HY-N9475 Betulonaldehyde Inhibitor / 否
HY-P10029 Sakura-6 Inhibitor / 否
HY-P10057 cpm-1285 Inducer / 否
HY-P10110 retro-inverso TAT-Beclin 1 (D-amino acid) Inducer / 否
HY-P10721 Plectasin Inhibitor / 否
HY-P10816 PACE4 Inhibitory peptide C23 / 否
HY-P11312 [S5K, F6Y, L9mL, M10Mox] neurokinin A (4–10) / 否
HY-P1259 PR-39 Inhibitor / 否
HY-P1290 PKA Inhibitor Fragment (6-22) amide Inhibitor / 否
HY-P1302A Orphanin FQ(1-11) TFA Agonist / 否
HY-P1949 Cyclic MKEY / 否
HY-P3102A GLP-1(32-36)amide TFA / 否
HY-P3707 Tumor targeted pro-apoptotic peptide Inducer / 否
HY-P4641 H-Trp-Phe-OH Inhibitor 99.87% 否
HY-P5130 Big endothelin-1 (rat 1-39) Ligand / 否
HY-P5808 Iota-conotoxin RXIA Agonist / 否
HY-P5890 YVAD-CHO Inhibitor / 否
HY-P5890A YVAD-CHO TFA Inhibitor / 否
HY-RS08425 MICAL1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-W009688 Dibutyl maleate 98.80% 否
HY-W040276 Diafen NN / 否
HY-W097106 (S)-3-N-Cbz-Amino-succinimide ≥97.0% 否
HY-W331017 1-Hexacosanoyl-sn-glycero-3-phosphocholine / 否
HY-W795264 FR900098 Inhibitor / 否
HY-100442S Paquinimod-d5 Inhibitor / 否
HY-100840 (S)-4C3HPG / 否
HY-101699A AMG-076 Antagonist / 否
HY-101775 9-Hydroxyellipticin Inhibitor / 否
HY-103163 (±)-5'-Chloro-5'-deoxy-ENBA Agonist / 否
HY-103388 NCX 466 Inhibitor / 否
HY-103567A Desmethyl-YM-298198 Antagonist / 否
HY-107567B Carcinine dihydrochloride Antagonist 99.39% 否
HY-109044S Tapinarof-d5 Agonist / 否
HY-114992 2-Propyl-2-pentenoic acid / 否
HY-116799 NSC 145669 Inhibitor / 否
HY-117446 AS-1669058 Agonist / 否
HY-118537 ICI 56780 Inhibitor / 否
HY-118802 4-Hydroxy DPT / 否
HY-118803 AS1468240 Inhibitor / 否
HY-119218 LH 1 / 否
HY-119955 Amflutizole Inhibitor / 否
HY-120450 CL-55 Inhibitor / 否
HY-120462 Genz-669178 Inhibitor / 否
HY-124290A Carotegrast methyl hydrochloride Antagonist / 否
HY-124499 RUC-1 Inhibitor / 否
HY-12580 RO5353 MDM2 Inhibitor / 否
HY-12610 Carbonic anhydrase inhibitor 27 Inhibitor / 否
HY-126170 Valanimycin Inhibitor / 否
HY-127014 Julimycin B2 Inhibitor / 否
HY-129318 MBX-1066 Inhibitor / 否
HY-129347 Lankacyclinol A Inhibitor / 否
HY-129577 Aplysin Inhibitor / 否
HY-134314 8-Nitro-cGMP Inducer / 否
HY-134579 Chaetomellic acid A Inhibitor / 否
HY-138100 Hyalodendrin Inhibitor / 否
HY-138289 4-acetoxy MPT / 否
HY-138291 Ethoxyquin dimer 98.70% 否
HY-139240 Cannabidihexol / 否
HY-147548 Keap1-Nrf2-IN-10 Inhibitor / 否
HY-161728 Antibacterial agent 223 Inhibitor / 否
HY-161935 6-(12-Tridecene-1-yl)-2,4-Dihydroxy benzoic acid Inhibitor / 否
HY-161937 Antibacterial agent 236 Inhibitor / 否
HY-164384 DFX117 / 否
HY-164462 BHA536 / 否
HY-164547 WHN-88 Inhibitor / 否
HY-165014 2C-I-FLY hydrochloride / 否
HY-168355 Δ8-THC methyl ether Ligand / 否
HY-168365 (±)-Pellotine hydrochloride / 否
HY-168368 exo-Tetrahydrocannabivarin Ligand / 否
HY-168629 FXR agonist 9 Inhibitor / 否
HY-168792 (±)-9-Nor-9α-hydroxy Hexahydrocannabinol / 否
HY-169858 Prostaglandin E2 Inhibitor 3 Inhibitor / 否
HY-170717 3-Methylnordiazepam / 否
HY-172335 C9-200 / 否
HY-21193R Perfluoropentanoic acid (Standard) / 否
HY-B0448S2 Phenytoin-d5 Inhibitor / 否
HY-B2085 Arsthinenol / 否
HY-N10346A Gluconapin / 否
HY-N11681 Microcystin-WR / 否
HY-N12171 Isoreserpiline Inhibitor / 否
HY-N12719 Isocampneoside I / 否
HY-N13715 Thalicminine / 否
HY-N13894 Auramycin A Inhibitor / 否
HY-N13895 Auramycin B Inhibitor / 否
HY-N14018 Glidobactin A Inhibitor / 否
HY-N14193 Estatin B Inhibitor / 否
HY-N14200 Maridomycin II Inhibitor / 否
HY-N14201 Maridomycin IV Inhibitor / 否
HY-N14202 Maridomycin V Inhibitor / 否
HY-N14203 Maridomycin VI Inhibitor / 否
HY-N14586 Roridin J / 否
HY-N14941 Phleomycin G Inhibitor / 否
HY-N15180 Corynantheidine / 否
HY-N9484S Menthofuran-13C2 / 否
HY-P0009S1 Cetrorelix-d10 Antagonist / 否
HY-P10200 CP7-FP13-2 Inhibitor / 否
HY-P4885 Glp-amyloid-β (3-40) peptide (human) / 否
HY-W188178 N-Mitrososarcosine / 否
HY-W369099 HJC0152 free base / 否
HY-W665796 N-Methyl-N-nitroso-2-propanamine / 否
HY-W681659 Flutoprazepam Inhibitor / 否
HY-109506S10 DPPC-13C3 / 否
抗体抑制剂 (7)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-P99123 Anti-Mouse CD28 Antibody (37.51) 95.00% 否
HY-P99148 Anti-Mouse/Rat/Rabbit TNF alpha Antibody (TN3-19.12) Inhibitor 95.00% 否
HY-P99129 Anti-Mouse CD8a Antibody (53-6.7) Inhibitor 95.00% 否
HY-P990282 Anti-Mouse CD24 Antibody (M1/69) Inhibitor ≥95.0% 否
HY-P99620 Firivumab Inhibitor 95.00% 否
HY-P990812 Anti-Mouse myeloperoxidase/MPO Antibody (6D1) Inhibitor / 否
HY-P991433 BIIB036 Activator / 否

直系同源

种属 基因名 来源 基因 ID
Felis catus MICAL1 VGNC VGNC:63493
Bos taurus MICAL1 VGNC VGNC:31457
Mus musculus MICAL1 MGD MGI:2385847
Rattus norvegicus MICAL1 RGD RGD:1309386
Canis familiaris MICAL1 VGNC VGNC:49758
Macaca mulatta MICAL1 VGNC VGNC:74547
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