1. Neuronal Signaling
  2. Monoamine Oxidase
  3. Osthenol

Osthenol (Synonyms: Ostenol)

目录号: HY-N2554
产品使用指南

Osthenol (Ostenol) 是从独活干根中分离得到的一种前酰化香豆素,是一种可逆的,选择性的竞争性人单胺氧化酶-A (hMAO-A) 抑制剂 (Ki=0.26 µM)。Osthenol 对重组 hMAO-A 具有潜在的选择性抑制作用,IC50为 0.74 µM,对hMAO-A和hMAO-B表现出较高的选择性指数。

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Osthenol Chemical Structure

Osthenol Chemical Structure

CAS No. : 484-14-0

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Description

Osthenol (Ostenol), a prenylated coumarin isolated from the dried roots of Angelica pubescens, is selective, reversible, and competitive human monoamine oxidase-A (hMAO-A) inhibitor (Ki=0.26 µM). Osthenol potently inhibits recombinant hMAO-A with an IC50 of 0.74 µM and shows a high selectivity index for hMAO-A versus hMAO-B[1].

IC50 & Target[1]

hMAO-A

0.26 μM (Ki)

hMAO-A

0.74 μM (IC50)

Molecular Weight

230.26

Formula

C₁₄H₁₄O₃

CAS No.

484-14-0

SMILES

O=C1C=CC2=CC=C(O)C(C/C=C(C)\C)=C2O1

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
  • 摩尔计算器

  • 稀释计算器

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

OsthenolOstenolMonoamine OxidaseMAOcoumarinselectivecompetitivedepressionInhibitorinhibitorinhibit

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产品名称:
Osthenol
目录号:
HY-N2554
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