1. Gene
  2. TYR - Tyr tyrosinase Gene

TYR - Tyr tyrosinase Gene

种属: Rattus norvegicus

基因 ID: 308800 | 基因类型: protein coding

关于 TYR

功能概要

Predicted to enable copper ion binding activity; protein homodimerization activity; and Tyrosinase activity. Involved in several processes, including response to UV; response to cAMP; and response to vitamin D. Located in cytosol and nucleus. Used to study oculocutaneous albinism. Human ortholog(s) of this gene implicated in melanoma (multiple); ocular albinism; oculocutaneous albinism (multiple); retinoschisis; and vitiligo. Orthologous to human TYR (Tyrosinase). [provided by Alliance of Genome Resources, Apr 2022]

TYR 基因产物(1)

mRNA Protein Name
NM_001107535.1 NP_001101005.1 tyrosinase precursor
基因本体论
  • 生物过程
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in pigmentation IMP
IMP: 通过突变表型推断
15760344 RGD
involved in response to UV IEP
IEP: 通过表达模式推断
6175546 RGD
involved in response to cAMP IEP
IEP: 通过表达模式推断
6175546 RGD
involved in response to vitamin D IEP
IEP: 通过表达模式推断
6175546 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

tyrosinase

直系同源

种属 基因名 来源 基因 ID
Homo sapiens TYR NCBI NCBI:7299
Canis familiaris TYR NCBI NCBI:403405
Macaca fascicularis TYR NCBI NCBI:102141480
Mus musculus TYR NCBI NCBI:22173
Susscrofa domestica TYR NCBI
Leporidae TYR NCBI
Macaca mulatta TYR NCBI NCBI:705792